Sökning: "microelectrode array"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden microelectrode array.

  1. 1. New Electrochemical Tools to Study Exocytosis

    Författare :Joakim Wigström; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; amperometry; QCM-D; micro electrode array; large dense core vesicles; chromaffin cells; PC-12 cells; microelectrode; exocytosis; electrochemical cytometry; electrochemical imaging; acetylcholine; endocytosis; nanoparticles; enzyme biosensor; microfabrication;

    Sammanfattning : The work described in this thesis has the focus on the development of new analytical tools to study processes related to cellular secretion (exocytosis) in cell models. Four novel techniques were developed, allowing new ways to study processes related to exocytosis, and gain previously unattainable knowledge. LÄS MER

  3. 2. Towards Better Understanding of Etiological Mechanisms at the Neuromuscular Junction

    Författare :Evgenii Bogatikov; Anna Rostedt Punga; Klas Kullander; Viktorija Kenina; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neuromuscular junction; Muscle cells; Microelectrode array; MicroRNA; Clinical Neurophysiology; Klinisk neurofysiologi; Biomedical Laboratory Science; Biomedicinsk laboratorievetenskap;

    Sammanfattning : The neuromuscular junction (NMJ) serves as a model for understanding the mechanisms that determine communication between neurons and their target cells. Disorders of the NMJ can be either autoimmune or genetic (hereditary). LÄS MER

  4. 3. Human iPSC-derived neuronal networks. Development and application for compound evaluation

    Författare :Julia Izsak; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human induced pluripotent stem cell; neuronal network; microelectrode array; in vitro;

    Sammanfattning : Research on human brain development and function in health and disease has been hampered by limited access to primary human tissue and limited translatability of animal studies. This knowledge gap is encouraging the use of human induced pluripotent stem cell (hiPSC)-derived neural in vitro models. LÄS MER

  5. 4. Microelectrode cluster technology for precise interactions with neuronal circuits. Towards highly specific adaptive deep brain stimulation

    Författare :Mohsin Mohammed; Neuronano Research Center (NRC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Neuro-electronic interfaceneural interface; neural interface; tissue reactions; deep brain stimulation; Adaptive DBS; biocompatibility; implantation method; neurosurgical tool;

    Sammanfattning : Neuro-electronic interfaces, which can be used for stable communication between neurons-computers over long periods of time, would be valuable for understanding and interacting with the nervous system. A major challenge has been to overcome the tissue reactions towards implanted electrodes. LÄS MER

  7. 5. The Mechanisms of Exocytosis Studied in Cells and Models with Amperometry

    Författare :Lisa J. Mellander; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Exocytosis; Electrochemistry; Cells; Cell models; Phospholipids;

    Sammanfattning : Exocytosis is the universal basis for neuronal communication, allowing the controlled release of neurotransmitter molecules from the presynaptic cell. Exocytosis has been widely studied in many systems. However, the details of this vital process are not fully understood. LÄS MER