Sökning: "microarrays"

Visar resultat 11 - 15 av 210 avhandlingar innehållade ordet microarrays.

  1. 11. Novel diagnostic microarray assay formats towards comprehensive on-site analysis

    Författare :Jesper Gantelius; Helene Andersson-Svahn; Christer Wingren; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; magnetic microbeads; gold nanobeads; microarrays; lateral flow; on-site diagnosis; SNPs; pestivirus; autoimmunity; contagious bovine pleuropneumonia; comsol multiphysics; finite element method; Microbiology; Mikrobiologi; Biochemistry; Biokemi;

    Sammanfattning : Advances in molecular methods for analyzing DNA, RNA and proteins in humans as well as in other animals, plants, fungi, bacteria or viruses have greatly increased the resolution with which we can study life’s complexity and dynamics on earth. While genomic, transcriptomic and proteomic laboratory tools for molecular diagnosis of disease are rapidly becoming more comprehensive, the access to such advanced yet often expensive and centralized procedures is limited. LÄS MER

  3. 12. Genetic and Epigenetic Characterisation of Breast Tumours

    Författare :Karolina Holm; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Breast cancer; PIK3CA; PTEN; PI3K pathway; CCND1; microarrays; molecular subtypes; DNA methylation; EZH2; H3K27me3; PRC2; histone modification;

    Sammanfattning : Breast tumours harbour a large amount of genetic and epigenetic alterations, which are associated with e.g. tumour aggressiveness, prognosis, and response to therapy. LÄS MER

  4. 13. Omics Data Analysis of Complex Diseases and Traits

    Författare :Saman Hosseini Ashtiani; Arne Elofsson; Dirk Repsilber; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Omics data; RNA-seq; Microarrays; Metabolomics; Network analysis; Psoriasis; E. coli; Hip osteoporosis; Lung adenocarcinoma; Spearman s correlation coefficient; LC-MS; PCA; DEG; PPI; biokemi med inriktning mot bioinformatik; Biochemistry towards Bioinformatics;

    Sammanfattning : Following the advent of the high-throughput techniques for producing massive omics data, new possibilities and challenges have also emerged in different fields of biology and medicine. Dealing with such data on different scales with different scopes such as genomics, transcriptomics, proteomics and metabolomics, demands appropriate data collection, preprocessing, statistical analysis, interpretation and visualization. LÄS MER

  5. 14. Sexual Conflict and Gene Expression in Drosophila melanogaster

    Författare :Paolo Innocenti; Edward Morrow; Göran Arnqvist; Andrew G Clark; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Sexual conflict; sexual selection; male-female coevolution; gene expression; transcriptome; microarrays; sexual dimorphism; Drosophila; Biology; Biologi; Biologi med inriktning mot zooekologi; Biology with specialization in Animal Ecology; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Sexual conflict is broadly defined as a conflict between the evolutionary interests of the two sexes. Depending on the genetic architecture of the traits involved, it can occur at the level of male-female interactions or take the form of selection acting to change the mean of a shared trait against the sign of its genetic correlation. LÄS MER

  7. 15. Metabolic Engineering of Xylose-Utilising Saccharomyces cerevisiae Strains. A Closer Look at Recombinant Strains Based on the Xylose Reductase-Xylitol Dehydrogenase Pathway

    Författare :Marie Jeppsson; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi; microarrays; cofactors; XK; XDH; XR; lignocellulose; xylose; ethanol; Saccharomyces cerevisiae; yeast;

    Sammanfattning : Saccharomyces cerevisiae produces ethanol efficiently from the hexose sugars in lignocellulose hydrolysates, but it can not utilise pentose sugars such as xylose and arabinose. Stable xylose-utilising S. LÄS MER