Sökning: "micro-RNA"
Visar resultat 6 - 10 av 19 avhandlingar innehållade ordet micro-RNA.
6. Quantification of Radiation Induced DNA Damage Response in Normal Skin Exposed in Clinical Settings
Sammanfattning : The structure, function and accessibility of epidermal skin provide aunique opportunity to study the DNA damage response (DDR) of a normaltissue. The in vivo response can be examined in detail, at a molecularlevel, and further associated to the structural changes, observed at atissue level. LÄS MER
7. PKB/Akt kinase localization and role in stemness maintenance in cancer
Sammanfattning : Cancer incidence rates have increased over the last decade. Currently available therapies are only moderately effective in targeting cancer cells. Established cancer treatment protocols fail to eliminate populations of cancer stem cells (CSCs), which develop resistance against the chemotherapeutic drugs and lead to cancer recurrence. LÄS MER
8. Characteristics and functions of thymic exosomes in human and mouse
Sammanfattning : Thymocytes develop in the thymus to become a functional pool of T-cells in the periphery. To achieve this, the thymocytes go through several steps of maturation and selection within the thymus. LÄS MER
9. Functional and Transcriptional Studies of Human Dopaminergic Neurons
Sammanfattning : Parkinson’s Disease (PD) is the most common movement disorder and second most common neurodegenerative disease. The principal hallmark of the pathology is represented by a loss of mesencephalic Dopaminergic neurons (mesDA) that reside in the Substantia Nigra pars compacta (SNpc). LÄS MER
10. TGF-B signaling in Neuroblastoma and Renal Cell Carcinoma
Sammanfattning : The tubular cells of the adult kidney are normally mitotically quiescent, in stark contrast to the massive regenerative capacity of the injured renal epithelium. In Paper I we characterized a new cell population of progenitor cells using ALDH as a selection marker. LÄS MER