Sökning: "micro-RNA"
Visar resultat 11 - 15 av 19 avhandlingar innehållade ordet micro-RNA.
11. Functional epigenetic analyses in the context of psychiatric health in adolescence
Sammanfattning : Adolescence is a unique and formative period for learning and developing skills and abilities for adulthood. The prevalence of mental health problems in adolescents is estimated to 10-20%, being a major risk for suicide, social and academic impairments. Suicide is the third leading cause of death in older adolescents (15-19 years). LÄS MER
12. Transcriptional control of CD4+ T lymphocytes
Sammanfattning : The immune system can respond to various types of pathogens such as bacteria, viruses, tumors and parasites. The ability to provide protection against different types of pathogens partly relies on development of alternative T effector cells with separate effector functions. LÄS MER
13. IDO gene expression induction by DNA methylation inhibitors
Sammanfattning : The aim was to study the effect of DNA methylation of CpG motifs in cancer cells and immune cells by use of the DNA methyltransferas (DNMT) inhibitor zebularine. In cancer cells it is known that genes can be silenced by chromosomal deletion(s). It is also known that genes can be silenced by DNA methylation or expression of micro-RNA. LÄS MER
14. miRNA and Asymmetric siRNA : Small RNAs with Large Effects on Bone Metabolism
Sammanfattning : RNA interference (RNAi) is a post-transcriptional gene silencing process elicited by double-stranded RNA, such as micro-RNA (miRNA) and small interfering RNA (siRNA). They are 18-25 nucleotide long, small non-coding RNAs acting as critical regulators in eukaryotic genome expression. LÄS MER
15. Essays on spatial point processes and bioinformatics
Sammanfattning : This thesis consists of two separate parts. The first part consists of one paper and considers problems concerning spatial point processes and the second part includes three papers in the field of bioinformatics. LÄS MER