Sökning: "metoclopramide"

Hittade 4 avhandlingar innehållade ordet metoclopramide.

  1. 1. The mode of action of the radiosensitizing analogs metoclopramide and nicotinamide

    Författare :Anders Olsson; Lund Wallenberg Neurocentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; medical instrumentation; metoclopramide; nicotinamide; apoptosis; radiosensitization; NAD; benzamide; DNA repair; Clinical physics; tomography; radiology; Klinisk fysiologi; radiologi; tomografi; medicinsk instrumentering;

    Sammanfattning : This thesis provides the first attempt to study the nicotinamides and benzamides from a mode of action point of veiw. Understanding the effects on DNA repair, cell cycle control (proliferation) and cell death from these agents and in combination with ionizing radiation, provides a new opportunity to logically develop better approaches to sensitize already existing therapies via for example induction of apoptosis or inhibition of DNA repair. LÄS MER

  3. 2. Experimental and clinical studies on the antiemetic effects of propofol

    Författare :Bengt Hammas; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; gastric emptying; gastric tone; orocecal transit time; propofol; dopamine; serotonin; morphine; postoperative nausea and vomiting; Kirurgi; Surgery; Kirurgi; anestesiologi; Anaesthesiology;

    Sammanfattning : Postoperative nausea and vomiting (PONV) is still a clinical problem and its incidence is unacceptably high. After the introduction of propofol as an agent for induction and maintenance of anesthesia, it was reported that the incidence of PONV was lower. It was also proposed that propofol possesses antiemetic effects. LÄS MER

  4. 3. Nausea and emesis in cancer chemotherapy : aspects of occurrence, assessment and treatment

    Författare :Sussanne Börjeson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cancer chemotherapy; cancer nursing; nausea; emesis; antiemetics; well-being;

    Sammanfattning : Nausea and emesis are two of the most distressing side-effects cancer patients may experience during chemotherapy. The general aim of this thesis was to acquire knowledge to be used for improving the care of cancer patients during chemotherapy, in particular for the prevention and palliation of chemotherapy-induced nausea and emesis. LÄS MER

  5. 4. The influence of status epilepticus on adeno-pituitary hormone secretion in man : with special reference to prolactin

    Författare :Ulla Lindbom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :epilepsy; status epilepticus; prolactin; growth hormone; cortisol; thyroidstimulating hormone TSH ; thyrotropin-releasing hormone TRH ; hypothalamic-pituitary axis;

    Sammanfattning : Epileptic seizures as well as antiepileptic drugs (AED) may interfere with the hypothalamic pituitary axis (HPA) and have neuroendocrine effects. A transient increase of prolactin (PRL) and cortisol in serum after generalised tonic-clonic or complex partial seizures has been one of the most consistent findings, although absences and myoclonic seizures, as well as seizures of very short duration, do not seem to affect PRL levels. LÄS MER