Sökning: "methylmercury"

Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet methylmercury.

  1. 1. Formation, uptake and bioaccumulation of methylmercury in coastal seas : a baltic sea case study

    Författare :Aleksandra Skrobonja; Erik Björn; Agneta Andersson; Anne L. Soerensen; Marc Amyot; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mercury; methylmercury; bioaccumulation; mesososm; isotope tracers; methylation; demethylation; stability constant; kinetic model; coastal sea; ICPMS; LC-MS MS;

    Sammanfattning : Methylmercury (MeHg) is a potent neurotoxin which can bioaccumulate to harmful levels in aquatic food webs. Methylmercury formation is a predominantly biotic process which involves phylogenically diverse microorganisms (e.g. iron- or sulfate-reducing bacteria). LÄS MER

  3. 2. Novel Endpoints To Unravel Developmental Neurotoxicity : From DNA methylation responses to methylmercury to the in vitro identification of endocrine disruptors

    Författare :Andrea Cediel-Ulloa; Joëlle Rüegg; Pamela J. Lein; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Developmental neurotoxicity; Methylmercury; DNA methylation; Endocrine disruptors; in vitro assay development; Biology with specialization in Environmental Toxicology; Biologi med inriktning mot miljötoxikologi;

    Sammanfattning : The developing brain is especially sensitive to environmental stressors due to its dependence on the precise spatiotemporal regulation of multiple signals, and the long time period required for its formation. Some chemicals can interfere with molecular and cellular processes driving brain development, including epigenetic processes such as DNA methylation. LÄS MER

  4. 3. Unraveling the importance of solid and adsorbed phase mercury speciation for methylmercury formation, evasion and bioaccumulation

    Författare :Sofi Jonsson; Erik Björn; Ulf Skyllberg; Erik Lundberg; Per Persson; Robert Mason; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mercury; methylmercury; aquatic systems; estuary; Hg; MeHg; bioaccumulation; methylation; demethylation; evasion; sediment; water; terrestrial sources; atmospheric sources; climate change; eutrophication;

    Sammanfattning : Monomethylmercury, MeHg, is formed under anoxic conditions in waters, sediments and soils and then bioaccumulated and biomagnified in aquatic food webs, negatively effecting both human and wildlife health. It is generally accepted that precipitation of mercury, Hg, and adsorption of Hg to e.g. LÄS MER

  5. 4. Mercury species transformations in marine and biological systems studied by isotope dilution mass spectrometry and stable isotope tracers

    Författare :Lars Lambertsson; Wolfgang Frech; John Munthe; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Analytical chemistry; Mercury; methylmercury; ethylmercury; Thimerosal; speciation; methylation; demethylation; brackish water sediment; natural waters; GC-ICP-MS; species-specific isotope dilution; isotope enriched tracers; Analytisk kemi; Analytical chemistry; Analytisk kemi; analytisk kemi; Analytical Chemistry;

    Sammanfattning : This thesis focuses on the implementation of species-specific isotope dilution (SSID) methodology and stable isotope tracers to determine mercury species occurrence and transformation processes in-situ and during sample treatment. Isotope enriched tracers of methyl-, ethyl- and inorganic mercury were synthesised and applied in different combinations to marine and biological samples. LÄS MER

  7. 5. In vitro cellular models for neurotoxicity studies : neurons derived from P19 cells

    Författare :Dina Popova; Jacobsson Stig O.P.; Anna Forsby; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurotoxicity; Neuronal cell culture; P19 cells; SH-SY5Y cells; βIII-tubulin; Methylmercury; Okadaic acid; Acrylamide; MDMA; Piperazine-derived designer drugs.;

    Sammanfattning : Humans are exposed to a variety of chemicals including environmental pollutants, cosmetics, food preservatives and drugs. Some of these substances might be harmful to the human body. LÄS MER