Sökning: "methylhexahydrophthalic anhydride"

Hittade 3 avhandlingar innehållade orden methylhexahydrophthalic anhydride.

  1. 1. Protein adducts in plasma as biomarkers of exposure to and risk of organic acid anhydrides

    Författare :Seema Rosqvist; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GC-MS; IgG; IgE; exposure-response; serum albumin; biological monitoring; Hexahydrophthalic anhydride; methylhexahydrophthalic anhydride; OEL; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Sammanfattning : Organic acid anhydrides (OAAs) are important industrial chemicals but also potent inducers of airways diseases. Many exposed workers develop specific IgE and IgG antibodies. Hexahydrophthalic anhydride (HHPA) and methylhexahydrophthalic anhydride (MHHPA) are two particularly sensitising OAAs. LÄS MER

  3. 2. Metabolism and Biological Monitoring of Organic Acid Anhydrides

    Författare :Christian Lindh; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; rats; human; distribution; analysis; biological monitoring; autoradiography; adducts; hemoglobin; plasma; urine; Hexahydrophthalic anhydride; methyltetrahydrophthalic anhydride; guinea pigs; Occupational health; industrial medicine; Yrkesmedicin; arbetsmiljömedicin;

    Sammanfattning : The aim of this thesis was to describe the metabolism and to develope methods for biological monitoring for two organic acid anhydrides (OAAs), namely hexahydrophthalic anhydride (HHPA) and methylhexa-hydrophthalic anhydride (MHHPA). The OAAs are reactive, low molecular weight chemicals used in vast quantities in the industry. LÄS MER

  4. 3. Protein Modifications by Low Molecular Weight Chemicals Inducing Airways Diseases

    Författare :Marina Jeppsson; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MSight; hemoglobin human serum albumin; nasal lavage; acrylates; organic acid anhydrides; persulfate; biomarkers adducts; mass spectrometry; MoDetect;

    Sammanfattning : Airways diseases are one of the most common health effects in the western world today. It has been shown that low molecular weight chemicals (LMWC) can cause airways diseases. The mechanisms for these diseases are not well known in most cases. Also, methods for biological monitoring of exposure are not available for many of these LMWC. LÄS MER