Sökning: "methods validation"

Visar resultat 21 - 25 av 724 avhandlingar innehållade orden methods validation.

1. 21. Mass Spectrometry and Affinity Based Methods for Analysis of Proteins and Proteomes

   Författare :Mårten Sundberg; Margareta Ramström; Jonas Bergquist; Christer Wingren; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mass spectrometry; proteomics; microarray; protein; antibody; antigen; affinity; validation; Kemi med inriktning mot analytisk kemi; Chemistry with specialization in Analytical Chemistry;

   Sammanfattning : Proteomics is a fast growing field and there has been a tremendous increase of knowledge the last two decades. Mass spectrometry is the most used method for analysis of complex protein samples. It can be used both in large scale discovery studies as well as in targeted quantitative studies. LÄS MER

3. 22. Detection and Characterisation of Salmonella in Animal Feed Samples by PCR-Based Methods

   Författare :Charlotta Löfström; Teknisk mikrobiologi; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; Livsmedelsteknik; Biotechnology; Bioteknik; Biokemisk teknik; Biochemical technology; Analytisk kemi; Analytical chemistry; mykologi; virologi; bakteriologi; Mikrobiologi; validation; Microbiology; bacteriology; virology; mycology; Salmonella; ribotyping; detection; animal feed; randomly amplified polymorphic DNA; pulsed-field gel electrophorsis; pre-PCR processing; PCR; polymerase chain reaction; genotyping;

   Sammanfattning : Animal feed is a recognised source of Salmonella enterica for farm livestock and may also indirectly cause infection in people consuming foods of animal origin. It is therefore important to have rapid, reproducible and specific methods for the detection of Salmonella in feed, and for the characterisation of strains for further epidemiological investigations or to trace the source of contamination in a production facility. LÄS MER

4. 23. Development and Validation of a Numerical Tool for the Aeromechanical Design of Turbomachinery

   Författare :María Angélica Mayorca; Torsten Fransson; Damian Vogt; Eric Seinturier; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; aeromechanical design; turbomachinery; numerical tool; reduced order modeling; mistuning; ROM; aero-structure coupling; CFD; FEM; methods; Mechanical energy engineering; Mekanisk energiteknik;

   Sammanfattning : In aeromechanical design one of the major rules is to operate under High Cyclic Fatigue (HCF) margins and away from flutter. The level of dynamic excitations and risk of HCF can be estimated by performing forced response analyses from blade row interaction forces or Low Engine Order (LEO) excitation mechanisms. LÄS MER

5. 24. Experimental Validation of a Phased Array Ultrasonic Testing Probe Model and Sound Field Optimization

   Författare :Xiangyu Lei; Chalmers tekniska högskola; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Phased array; Sound field optimization; Experiments; Validation;

   Sammanfattning : New manufacturing technologies are developed to facilitate flexible product designs and production processes. However, the quality of the final products should not be compromised, especially for safety prioritized industries, e.g. aerospace industry. LÄS MER

7. 25. Validation of antibodies for protein profiling : A study using immunohistochemistry on tissue microarrays

   Författare :Linda Paavilainen; Fredrik Pontén; Ola Nilsson; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; antibody validation; monospecific antibodies; protein profiling; immunohistochemistry; tissue microarrays; western blot; fixatives; Pathology; Patologi; Pathology; patologi;

   Sammanfattning : The field of proteomics has rapidly expanded due to the completion of the human genome sequence. This thesis validates affinity-purified monospecific antibodies of polyclonal origin, for protein profiling in a broad spectrum of normal tissues and cells. LÄS MER