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Visar resultat 1 - 5 av 7 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Species specific susceptibility testing for ß-lactam antibiotics. With special reference to staphylococci

   Författare :Ann Cathrine Petersson; Avdelningen för medicinsk mikrobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; mycology; Mikrobiologi; virology; bacteriology; beta-lactamase; staphylococcus; methicillin resistance; Microbiology; mecA susceptibility testing; virologi; mykologi;

   Sammanfattning : The main objective of this thesis was to identify methods for the detection of ß-lactam resistance in staphylococci, bacteria often causing nosocomial infections. Detection of ß-lactam resistance in these species is difficult due to strong regulation of genes encoding for the two main resistance mechanisms, ß-lactamase production and the penicillin-binding protein (PBP) 2?. LÄS MER

3. 2. Molecular epidemiology of coagulase-negative staphylococci in hospitals and in the community

   Författare :Micael Widerström; Johan Wiström; Tor Monsen; Anders Sjöstedt; Bo Söderquist; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; staphylococcus epidermidis; staphylococcus saprophyticus; electrophoresis; gel; pulsed-field; genetic diversity; methicillin-resistance; UTI; drug resistance; multiple; bacterial; epidemiology; molecular; cross infection; molecular sequence data; Medical microbiology; Medicinsk mikrobiologi; Clinical bacteriology; Klinisk bakteriologi; Infectious diseases; Infektionssjukdomar; Clinical Bacteriology; klinisk bakteriologi; mikrobiologi; Microbiology; Infectious Diseases; infektionssjukdomar;

   Sammanfattning : Background Coagulase-negative staphylococci (CoNS) and in particular Staphylococcus epidermidis have emerged as major pathogens primarily causing nosocomial infections in patients with indwelling medical devices. These infections are often caused by multidrug-resistant strains of S. epidermidis (MDRSE). LÄS MER

4. 3. Development of an Ultrasensitive Capacitive DNA-sensor: A promising tool towards microbial diagnostics

   Författare :Ally Mahadhy; Bioteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capacitive DNA-sensor; Enterobacteriaceae; mecA gene; Methicillin resistance; automated sequential injection analysis; sandwichhybridization; elevated temperature; polytyramine;

   Sammanfattning : Fast and sensitive detection of pathogenic microbial cells is a highly important task in medical diagnostics, environmental analysis and evaluation of food safety. Accordingly, the idea of microorganism identification by the recognition of specific DNA sequence using electrochemical technique is one of the leading researches in the development of diagnostic devices. LÄS MER

5. 4. Studies on two bacterial resistance mechanisms to β-lactam antibiotics : extended spectrum β-lactamases in Klebsiella oxytoca and methicillin resistance in staphylococci

   Författare :Shang Wei Wu; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Eleven clinical isolates of Klebsiella oxytoca from Stockholm hospitals were found to be resistant to aztreonam and cefuroxime (MIC > 16 mg/L). The resistance was caused by a ß-lactamase with pI 5.25 and designated KH. Assay of the substrate profiles revealed that the KH ß-lactarnase was similar to the chromosomally encoded OXY-2 ß-lactamase. LÄS MER

7. 5. Epidemiological and molecular biological studies of multi-resistant methicillin-susceptible Staphylococcus aureus

   Författare :Maria Lindqvist; Anita Hällgren; Barbro Isaksson; Lennart E. Nilsson; Christina Åhrén; Linköpings universitet; []
   Nyckelord :;

   Sammanfattning : Antibiotic resistance is increasingly recognised as a major problem and threat. During the last decades Gram-positive bacteria in general, and methicillin-resistant Staphylococcus aureus (MRSA) in particular, have been in focus both concerning matters of antibiotic resistance and as pathogens causing health care-associated (nosocomial) infections. LÄS MER