Sökning: "methamphetamine"

Hittade 3 avhandlingar innehållade ordet methamphetamine.

  1. 1. The non-human primate as a model of human Parkinsonism

    Detta är en avhandling från Stockholm : Karolinska Institutet, Biosciences and Nutrition

    Författare :Alison McCormack; Karolinska Institutet.; Karolinska Institutet.; [2006]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; substantia nigra; aging; neuromelanin; MPTP; alpha-synuclein; levodopa; dyskinesia; methamphetamine;

    Sammanfattning : The motor deficits seen in Parkinson s disease (PD) are the result of a loss of catecholaminergic neurons from the substantia nigra (SN) and the associated loss of striatal dopamine. Clinical signs become evident once striatal dopamine levels decline by at least 70-80% and nigral cell numbers by 40%, and worsen with increased duration of the disease. LÄS MER

  2. 2. Analytical and Toxicological Aspects of Drug Incorporation into Human Hair

    Detta är en avhandling från Linköping : Linköpings universitet

    Författare :Robert Kronstrand; Pascal Kintz; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN;

    Sammanfattning : The overall purpose of this thesis was to develop analytical methods for the determination of drugs and melanin content of human hair for practical use in forensic and clinical toxicology. The thesis consists of five papers, two of which are controlled single dose studies where codeine or selegiline were administered to healthy volunteers. LÄS MER

  3. 3. Biochemical and pharmacological studies of transmethylation mechanisms in the central nervous system

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Mohammed Saleh Yassin; [1999]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; clioquinol; dementia; L-methionine S-adenosyltransferase; Parkinson s disease; S-adenosylhomocysteine; S-adenosylmethionine; schizophrenia; subacute myelo-optic neuropathy SMON ; vitamin B12 cyanocobalamin and neuroleptics; Neurovetenskap; MEDICINE Dermatology and venerology; clinical genetics; internal medicine Internal medicine Neurology; MEDICIN Dermatologi och venerologi; klinisk genetik; invärtesmedicin Invärtesmedicin Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : Transmethylation is a biochemical process that involves the transfer of a methyl group from a donor to an acceptor compound. Transmethylation reactions are involved in the biosynthesis of nucleic acids, proteins,phospholipids and catecholamines and are therefore essential for the survival of all living organisms. LÄS MER