Sökning: "methadone"

Visar resultat 16 - 20 av 21 avhandlingar innehållade ordet methadone.

  1. 16. Improving maintenance treatment of heroin addiction : the role of buprenorphine

    Författare :Karl Johan Kakko; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Heroin addiction is a condition with high morbidity and mortality. The discovery of Methadone Maintenance Treatment (MMT) by Dole and co-workers 1964 represented the first major advance in the treatment of this condition. Through the work of Gunne et al in Uppsala, MMT was implemented in Sweden already in 1966. LÄS MER

  3. 17. Long-term Effects of Opioids in the Treatment of Chronic Pain : Investigation of Problems and Hazards on Clinical, Biochemical, Cellular and Genetic Levels

    Författare :Annica Rhodin; Torsten Gordh; Fred Nyberg; Mats Stridsberg; Mats Enlund; Harald Breivik; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; opioid; chonic pain; long-term opioid treatment; Anaesthetics; Anestesiologi; Anestesiologi; Anaesthesiology;

    Sammanfattning : After two decades of liberal prescribing of opioids, there has been an increasing recognition of problems connected to the prolonged use of opioids for chronic pain. The aim of my thesis was to explore some consequences of long-term opioid treatment for chronic pain such as problematic opioid use, endocrine disorders, tolerance and genetic variations in pain and opioid response. LÄS MER

  4. 18. Placebo, alcohol and flumazenil provocations : subjective and objective registrations in psychopharmacological experiments

    Författare :Lars Saxon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Abuse and dependency of alcohol or drugs is a major problem today, with severe implications for society as well as for the individual. Treatment is often characterised by hard work and the road to recovery is (among other problems) paved with acute and protracted withdrawal symptoms as well as relapse. LÄS MER

  5. 19. Mass spectrometry in the search for new drugs of abuse : method development and clinical application

    Författare :Helena Nordgren; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Clinical drug testing using immunochemical screening methodology is limited regarding which analytes are covered. In this thesis, liquid chromatography was investigated as an alternative to immunochemical screening. LÄS MER

  7. 20. Risk behaviour and prevention of blood borne infections among injecting drug users

    Författare :Lillebil Nordén; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : In Stockholm County the two major injecting drugs are amphetamine and heroin, injected by about 9 000 persons almost every day. There is no access to needle and syringe program and about 1000 patients are in substitution programs, mostly Methadone and Burprenorphine programs. LÄS MER