Sökning: "metalloproteinase"

Visar resultat 6 - 10 av 102 avhandlingar innehållade ordet metalloproteinase.

1. 6. Inflammatory Markers, Respiratory Diseases, Lung Function and Associated Gender Differences

   Författare :Inga Sif Ólafsdóttir; Christer Janson; Anders Blomberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; C-reactive protein; matrix metalloproteinase-9; tissue inhibitor of metalloproteinase-1; COPD; FEV1; FVC; lung function; systemic inflammation; gender differences; Lungmedicin; Lung Medicine;

   Sammanfattning : Systemic inflammation is associated with impaired lung function. Inflammation is part of asthma and chronic obstructive pulmonary disease (COPD), but the local and systemic inflammatory pattern differs. LÄS MER

3. 7. Role of platelets and neutrophils in regulating trypsinogen activation and tissue damage in acute pancreatitis

   Författare :Aree Abdulla; Kirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease activation; adhesion molecule; chemokine; intravital flourecence microscopy; matrix metalloproteinase.;

   Sammanfattning : Acute pancreatitis is an inflammatory disease characterized by a diverse spectrum of clinical presentations ranging from a mild and self-limiting to a severe and systemic disorder. The relationship between inflammation and proteolytic activation in pancreatitis is an elusive issue. LÄS MER

4. 8. Matrix metalloproteinases in natural killer cells. Expression of MMPs, IL-2 activation and killer cell interactions with Matrigel® and model tumours

   Författare :Per Albertsson; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Protease; matrix metalloproteinase; killer cell; IL-2; Matrigel; B16 melanoma; tumour infiltration; invasion assay; zymography; Western blot; RT-PCR; light microscopy; fluorescence; electron microscopy;

   Sammanfattning : Introduction: IL-2 activated natural killer (A-NK) cells can recognize malignant cells and exert tumouricidal activities by multiple mechanisms that require close contact with the target cells. Upon adoptive transfer, some A-NK cells accumulate in tumours by migrating from the vascular bed to a position inside the malignant tissue, forming close contacts with target cells. LÄS MER

5. 9. Matrix metalloproteinases in Helicobacter inducedgastritis

   Författare :Philip Bergin; Göteborgs universitet; []
   Nyckelord :Helicobacter pylori; Helicobacter felis; Matrix metalloproteinase; macrophage; ; Gastritis;

   Sammanfattning : Helicobacter pylori infects the stomach and areas of gastric metaplasia in the duodenum. Theinfection leads to peptic ulcers or gastric cancers in 10-20% of infected individuals, while themajority are more or less asymptomatic. However, active chronic gastritis develops in all infectedindividuals, often in association with atrophic gastritis. LÄS MER

7. 10. Crosstalk between colorectal cancer cells and tumour-associated macrophages

   Författare :Yuan Zhang; Malmö Cellpatologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CD47; tumour-associated macrophage; matrix metalloproteinase; cell migration; colon cancer;

   Sammanfattning : Colorectal cancer (CRC) is the third most common cancer and the fourth leading cause of death from cancer worldwide. People suffering from inflammatory bowel disease, such as Crohns’ disease and ulcerative colitis, are at an increased risk of developing CRC. The development of CRC is highly influenced by the tumour microenvironment. LÄS MER