Sökning: "metal-catalysed transformation"

Hittade 4 avhandlingar innehållade orden metal-catalysed transformation.

  1. 1. Transition metal-catalysed enol formation from allylic alcohols : Isomerisation, C−C and C−F bond formations

    Författare :Nanna Ahlsten; Hans Adolfsson; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : This thesis describes the isomerisation of allylic alcohols into enols and enolates catalysed by transition metal complexes. The transformation has been used to prepare both unsubstituted and α-substituted carbonyl compounds. Significant attention has been given to the mechanistic aspects of the reactions. LÄS MER

  2. 2. Enzymes as catalysts in synthesis of enantiomerically pure building blocks : secondary alcohols bearing two vicinal stereocenters

    Författare :Rong Liu; Hans-Erik Högberg; Torbjörn Norin; Thorleif Anthonsen; KTH; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; enzyme; kinetic resolution; enantioselectivity; lipase; diastereoselectivity; epimerisation; metal-catalysed transformation; intramolecular alkylation.; Chemistry; Kemi;

    Sammanfattning : Enzymes as tools in organic synthesis have provided enormous advantages. This thesis deals with the applications of enzymes in the kinetic resolutions of racemic compounds. The stereochemistry of chiral compounds and the kinetics of α/β hydrolase lipases are presented. LÄS MER

  3. 3. Transition metal-catalysed hydrogen transfer processes for C-C and C-N bond formation : Synthetic studies and mechanistic investigations

    Författare :Agnieszka Bartoszewicz; Belen Martin-Matute; Martin Albrecht; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; hydrogen transfer; catalysis; transition metal; organisk kemi; Organic Chemistry;

    Sammanfattning : This thesis focusses on synthetic studies and mechanistic investigations into reactions involving hydrogen-transfer processes.In the first part, the development of an efficient method for the synthesis of β-hydroxy ketones (aldols) and β-amino ketones (Mannich products) from allylic alcohols and aldehydes is described. LÄS MER

  4. 4. C–H activation through late transition metal cyclometallation. Addressing selectivity and reactivity problems

    Författare :Mikhail Kondrashov; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; C—H activation; cyclometallation; pincer ligands; anion exchange; bimetallic complexes; oxidative functionalisation;

    Sammanfattning : The ligand-directed C—H activation relies on a coordinating donor atom being in proximity to the C—H bond activated. Cyclometallation of 2-(1-naphthyl)-pyridine – a substrate containing both γ- and δ-positions in proximity to the directing nitrogen atom – was studied. LÄS MER