Sökning: "metal-binding domain"
Visar resultat 1 - 5 av 12 avhandlingar innehållade orden metal-binding domain.
1. Structural studies of metal-binding proteins revealing dynamic behaviour
Sammanfattning : The Mg2+ and Mn2+ structures of calbindin D9k have been determined and they reveal a conformational change compared to the structures of apo and (Ca2+)2-calbindin D9k. These findings are unique, since normally calcium and not magnesium is known to induce conformational changes of EF-hand proteins. LÄS MER
2. Engineering of staphylococcal surfaces for biotechnological applications
Sammanfattning : The engineering of bacterial surfaces has in recent yearsattracted a lot of attention with applications in manydifferent areas of bioscience. Here we describe the use of twodifferent surface display systems for the gram-positivebacteria Staphylococcus carnosus and Staphylococcus xylosus invarious biotechnological applications. LÄS MER
3. Engineering Yeast for Functional Analysis of Human Cu Transport Proteins
Sammanfattning : ABSTRACT Copper (Cu) is an important trace element that plays a vital role in several biological processes. Many proteins that are involved in various biochemical pathways require Cu as a cofactor. LÄS MER
4. Metal Binding Tags - Characterisation, Use in Bioseparation and Applications of Green Fluorescent Fusion Proteins
Sammanfattning : Most of the recombinant proteins produced nowadays are fused to affinity tags, in order to facilitate their purification through affinity chromato-graphy. Out the different tags available, poly-histidine tags are among the most commonly used and can help purification through immobilised metal ion affinity chromatography (IMAC). LÄS MER
5. Development of a Yeast Model for Functional Analysis of Human Copper Transport Proteins
Sammanfattning : ABSTRACT Copper (Cu) is an important trace element that plays a vital role in several biological processes. It mediates numerous biochemical functions to maintain cellular homeostasis making it an essential metal for sustaining life. LÄS MER