Sökning: "metal ion switch"

Hittade 4 avhandlingar innehållade orden metal ion switch.

  1. 1. Poly(A)-Specific Ribonuclease (PARN)

    Författare :Yan-Guo Ren; Eric Westhof; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Poly A -specific ribonuclease; PARN; deadenylation; processive; oligomeric; cap interacting; aminoglycoside; active site; FE2 -mediated cleavage; metal ion switch; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Degradation of the mRNA 3'-end located poly(A) tail is an important step for mRNA decay in mammalian cells. Thus, to understand mRNA decay in detail, it is important to identify the catalytic activities involved in degrading poly(A). LÄS MER

  2. 2. Intramolecular electron transfer in DNA and ruthenium(II) systems

    Författare :Johan Olofsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; solvent relaxation; light switch effect; dppz; electron transfer and hydrogen bond;

    Sammanfattning : When ruthenium(II) complexes with heteroaromatic ligands absorb light, an electron is pushed from the metal ion out into one of the ligands, a process called metal-to-ligand-charge-transfer (MLCT). The resulting excited state can be used to initiate further electron transfer processes, or it can decay relatively slow back into the ground state with the emission of light. LÄS MER

  3. 3. Mechanism Studies of Catalytic RNA, and RNA and DNA Model Compounds

    Författare :Ethel Pettersson; Eric Westhof; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : This thesis describes mechanism studies of transesterifications of phosphate esters. The aim of the studies concerns two fields. First, the catalytic mechanism that group I introns use in self-splicing. The focus was on metal ion coordinating groups at the catalytic site. LÄS MER

  4. 4. Gene expression studies in human astrocytoma, with emphasis on oncostatin M induced effects

    Författare :Annika Krona; Göteborgs universitet; []
    Nyckelord :Brain tumors; astrocytoma; glioblastoma multiforme; oncostatin M OSM ; STAT; microarray;

    Sammanfattning : Brain tumors comprise about one percent of all cancers and astrocytoma is the most common primary brain malignancy. According to the World Health Organization system, the astrocytomas are divided into four grades according to degree of malignancy. Grade I, pilocytic astrocytoma (PA), is the least malignant form and most often affects children. LÄS MER