Sökning: "metagenomic sequencing"

Visar resultat 1 - 5 av 32 avhandlingar innehållade orden metagenomic sequencing.

  1. 1. Technologies for Single Cell Genome Analysis

    Författare :Erik Borgström; Afshin Ahmadian; Sten Linnarsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA; sequencing; single molecule; single cell; whole genome amplification; exome sequencing; emulsions; barcoding; phasin; Biotechnology; Bioteknologi;

    Sammanfattning : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. LÄS MER

  3. 2. Statistical analysis of metagenomic data

    Författare :Viktor Jonsson; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Metagenomics; Statistical methods; Hierarchical Bayesian models; Statistical power; False discovery rate; Environmental genomics; Generalized linear models; Count data; Environmental genomics;

    Sammanfattning : Metagenomics is the study of microbial communities on the genome level by direct sequencing of environmental and clinical samples. Recently developed DNA sequencing technologies have made metagenomics widely applicable and the field is growing rapidly. LÄS MER

  4. 3. Human papillomaviruses of skin and genital lesions

    Författare :Hanna K Johansson; Malmö Klinisk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; condylomas; ASCUS; CIN1; non-melanoma skin cancer; metagenomic sequencing; PCR;

    Sammanfattning : Around 5% of all cancer cases worldwide are caused by human papillomavirus (HPV) which has been established as the cause of cervical cancer and genital warts (condylomas). Cutaneous HPV types have been weakly associated with non-melanoma skin lesions such as squamous cell carcinoma (SCC) and actinic keratosis (AK). LÄS MER

  5. 4. Microbial DNA Sequencing in Environmental Studies

    Författare :Yue Hu; Anders Andersson; Jürg Logue; Joakim Lundeberg; Marja Tiirola; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; DNA sequencing; Metabarcoding; Microbial ecology; Baltic Sea; Microbial community; Illumina; Oxford Nanopore; Source tracking; Stormwater; Bioteknologi; Biotechnology;

    Sammanfattning : The field of microbial ecology has just entered a new era of rapid technological development and generation of big data. The high-throughput sequencing techniques presently available provide an opportunity to extensively inventorize the blueprints of life. LÄS MER

  7. 5. Analysis of large-scale metagenomic data

    Författare :Fredrik Boulund; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; metagenomics; DNA analysis; big data; antibiotic resistance; hidden Markov models; high-performance computing; distributed computing; distributed computing;

    Sammanfattning : The topic of this thesis is the analysis of large data sets of DNA sequence data produced from modern high-throughput DNA sequencing machines. Using such machines to sequence the genetic content of a microbial community produces a metagenome. This thesis comprises three research papers, all connected to the study of large metagenomic data sets. LÄS MER