Sökning: "metabotropic glutamate receptor"
Visar resultat 1 - 5 av 24 avhandlingar innehållade orden metabotropic glutamate receptor.
1. Beyond AMPA and NMDA: Slow synaptic mGlu/TRPC currents : Implications for dendritic integration
Sammanfattning : In order to understand how the brain functions, under normal as well as pathological conditions, it is important to study the mechanisms underlying information integration. Depending on the nature of an input arriving at a synapse, different strategies may be used by the neuron to integrate and respond to the input. LÄS MER
2. Neuromodulation within a spinal locomotor network : role of metabotropic glutamate receptor subtypes
Sammanfattning : The metabotropic glutamate receptors, mGluRs, are G-protein coupled receptors. They consist of eight cloned subtypes, which are divided into three groups depending on the amino acid sequence similarity, pharmacology and their signal pathways. LÄS MER
3. Behavioural and biochemical pharmacology of adenosine/dopamine receptor/receptor interaction
Sammanfattning : The neurotransmitter dopamine seems to be involved in neuropsychiatric diseases such as schizophrenia and Parkinson's disease. Direct blockade of dopamine receptors of the D2 subtype has been the hallmark of pharmacotherapy for schizophrenia since early 1950s. LÄS MER
4. On the role of metabotropic glutamate receptors in motor control : analysis of synaptic, cellular and network properties
Sammanfattning : The organization of neurons into neuronal networks is a basic feature of the central nervous system. An understanding of the function of neuronal networks requires knowledge on both synaptic connectivity and cellular properties. LÄS MER
5. Mechanisms in Tendon Healing : Pain, Biomarkers and the Role of Mast Cells
Sammanfattning : Tendon injuries and tendinopathy are common disorders, but the underlying mechanisms are not well understood. The overall aim of this thesis was to better understand the mechanisms underlying tendon healing, pain, and inflammation. LÄS MER