Sökning: "metabolomics"

Visar resultat 6 - 10 av 144 avhandlingar innehållade ordet metabolomics.

  1. 6. Nutritional metabolomics: The search for dietary exposure variables

    Författare :Millie Rådjursöga; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; metabolomics; nutrition; NMR; serum; urine; postprandial; dietary intake;

    Sammanfattning : To establish associations and causation between diet and health, objective and reliable methods are needed to measure dietary exposure. Metabolomics provide an unbiased tool for exploring the modulation of the human metabolome in response to food intake. LÄS MER

  3. 7. Proteomics and metabolomics in biological and medical applications

    Författare :Liudmila Shiryaeva; Wolfgang P. Schröder; Pernilla Wikström; Peter Roepstroff; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; 2D-DIGE; biomarkers; cold-acclimation; conifer; freezing tolerance; GC-MS; metabolomics; multiple hypothesis test; multivariate analysis; OPLS-DA; Picea obovata; plasma; prostate cancer; proteomics; ProteoMiner; Siberian spruce;

    Sammanfattning : Biological processes in living organisms consist of a vast number of different molecular networks and interactions, which are complex and often hidden from our understanding. This work is focused on recovery of such details for two quite distant examples: acclimation to extreme freezing tolerance in Siberian spruce (Picea obovata) and detection of proteins associated with prostate cancer. LÄS MER

  4. 8. Diagnosis of acute and chronic enteric fever using metabolomics

    Författare :Elin Näsström; Henrik Antti; Anders Johansson; Peter Spégel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Enteric fever; Salmonella; chronic carriers; metabolomics; diagnosis; biomarkers; multivariate data analysis; GCxGC-MS; GC-MS; LC-MS;

    Sammanfattning : Enteric (or typhoid) fever is a systemic infection mainly caused by Salmonella Typhi and Salmonella Paratyphi A. The disease is common in areas with poor water quality and insufficient sanitation. Humans are the only reservoir for transmission of the disease. LÄS MER

  5. 9. Black mustard and the butterfly effect : metabolomics of plant-insect interactions under multiple stress conditions

    Författare :Stefano Papazian; Benedicte Albrectsen; Edward Farmer; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; plant physiology; metabolomics; glucosinolates; multiple stress; ozone; Brassica nigra; Pieris brassicae; Brevicoryne brassicae; biology; biologi; Environmental Science; miljövetenskap; molekylärbiologi; Molecular Biology; Entomology; entomologi;

    Sammanfattning : One main goal of ecological research is to understand nature´s complexity, in order to predict the potential impact of environmental perturbations. In this thesis, I investigate the ecological interactions between some of the most ancient organisms living on our planet: plants and insects. LÄS MER

  7. 10. Analytical method development in liquid chromatography- mass spectrometry based metabolomics

    Författare :Ida Erngren; Mikael Hedeland; Curt Pettersson; Torbjörn Arvidsson; Gérard Hopfgartner; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Analytical pharmaceutical chemistry; metabolomics; liquid chromatography; mass spectrometry; hydrophilic interaction liquid chromatography; Analytical Pharmaceutical Chemistry; Analytisk farmaceutisk kemi;

    Sammanfattning : Metabolomics is the analytical field which aims at analyzing all small molecules, metabolites, in a biological system simultaneously. Currently no analytical methods are able to capture the entire metabolome, therefore, the analytical methods are often developed to be as general as possible. LÄS MER