Sökning: "metabolic ratio"

Visar resultat 16 - 20 av 216 avhandlingar innehållade orden metabolic ratio.

  1. 16. Metabolic signals in the regulation of insulin release

    Författare :Jude T Deeney; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :insulin-secreting cells; glucose metabolism; ATP ADP ratio; cytoplasmic free Ca2 concentration; long-chain acyl-CoA; protein kinase C; insulin secretion; serotonin release; permeabilized cells; intracellular Ca2 handling; exocytosis;

    Sammanfattning : In the present thesis, an attempt was made to elucidate the role of some of the glucose-induced intracellular metabolic effector signals in insulin secretion and to develop new applications that will enable further investigations of oscillatory signalling and secretion from pancreatic ß-cells. The sequence of early metabolic and ionic events was examined in clonal pancreatic insulin secreting cells (HIT) in response to glucose stimulation. LÄS MER

  3. 17. Adipose markers of metabolic outcome after weight loss

    Författare :Daniel Eriksson Hogling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Adipose tissue is closely linked to metabolic disturbances in obesity. Bariatric surgery such as roux-en-Y gastric bypass (RYGB) remains the most effective treatment of obesity and obesity-related disease. LÄS MER

  4. 18. Atherosclerosis in middle-aged men. A prospective study with focus on factors related to the metabolic syndrome

    Författare :Karin Wallenfeldt; Göteborgs universitet; []
    Nyckelord :apolipoproteins; atherosclerosis; C-reactive protein; insulin resistance; intima-media thickness; LDL cholesterol; longitudinal study; metabolic syndrome X; smokeless tobacco; ultrasonography;

    Sammanfattning : The metabolic syndrome (MetS) is a clustering of cardiovascular disease CVD) risk factors. Pro-spective studies have demonstrated that patients with MetS are about three times more likely to experience CVD events than those without MetS. Up to one third of the adult population seems to be affected worldwide. LÄS MER

  5. 19. Novel epidemiologic and mechanistic aspects of the metabolic syndrome

    Författare :Justo Sierra-Johnson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Introduction: The metabolic syndrome is a cluster of cardiometabolic risk factors that increase risk of developing cardiovascular disease. Its prevalence continues to rise worldwide and it is becoming a public health burden. The aim of my thesis was to help elucidate some of the epidemiologic and mechanistic aspects behind the metabolic syndrome. LÄS MER

  7. 20. Long-term metabolic effects of a high birth weight

    Författare :Inger W Johnsson; Jan Gustafsson; Fredrik Ahlsson; Maria Lundgren; Ola Nilsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Body composition; Cardiovascular risk factors; Gestational diabetes; Glucose tolerance; High birth weight; Insulin sensitivity; Large for gestational age; Obesity; Offspring macrosomia; Type 2 diabetes; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

    Sammanfattning : The intrauterine environment influences foetal growth as well as future response to risk factors for disease. This occurs partly through epigenetic mechanisms. Thus, birth weight is a possible risk marker of adult disease. LÄS MER