Sökning: "mesenchymal tumor"
Visar resultat 1 - 5 av 87 avhandlingar innehållade orden mesenchymal tumor.
1. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation
Sammanfattning : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. LÄS MER
2. Platelets – Multifaceted players in tumor progression and vascular function
Sammanfattning : Platelets play a crucial role for blood hemostasis, the process that prevents bleeding. In addition, platelets have been demonstrated to promote cancer progression and cancer related complications like metastasis and thrombosis. LÄS MER
3. Genetic Characterization of Bone and Soft Tissue Tumors
Sammanfattning : Bone and soft tissue tumors (BSTT) constitute a heterogeneous group of neoplasms of mesenchymal and neuroectodermal origin. Although many BSTT are rare, it has become clear that BSTT are characterized by recurrent acquired chromosomal aberrations, and the general aim of this thesis have been to apply molecular genetic and molecular cytogenetic techniques to further characterize recurrent breakpoints and deletions, and to search for candidate target genes. LÄS MER
4. Importance of Hyaluronan-CD44 Signaling in Tumor Progression : Crosstalk with TGFβ and PDGF-BB Signaling
Sammanfattning : In order for solid tumors to metastasize, tumor cells must acquire the ability to invade the surrounding tissue and intravasate into blood- or lymph vessels, survive in the circulation and then extravasate at a distant site to form a new tumor. Overexpression of the glycosaminoglycan hyaluronan, and its adhesion receptor CD44, correlate with breast cancer progression. LÄS MER
5. Molecular factors influencing epithelial-mesenchymal transition in breast cancer
Sammanfattning : Epithelial-mesenchymal transition (EMT) is a developmental process defined by loss of epithelial characteristics and acquisition of mesenchymal phenotype. EMT or similar processes are also implicated in carcinoma cell invasion and the progression of breast carcinoma to metastasis. LÄS MER