Sökning: "mesenchymal stem cells"

Visar resultat 6 - 10 av 128 avhandlingar innehållade orden mesenchymal stem cells.

1. 6. Keratinocytes and Adipose-derived mesenchymal stem cells : The heir and the spare to regenerative cellular therapies for difficult-to-heal skin wounds

   Författare :Hady Shahin; Ahmed Taher Elserafy; Moustafa Elmasry; Folke Sjöberg; Ingrid Steinvall; Daniel Nowinski; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Keratinocytes; ATMP; Bio-production; Adipose-derived mesenchymal stem cells; Wound healing;

   Sammanfattning : Cell-based therapy is considered as Advanced Therapy Medicinal Product, (ATMP), which had increasingly stricter regulations in the last decade. The cells must be produced according to the ‘Guidelines on Good Manufacturing Practice (GMP) specific to Advanced Therapy Medicinal Products’, adopted by the European Medicines Agency (EMA). LÄS MER

3. 7. The osteogenic potential of human mesenchymal stem cells: Novel markers and key factors for differentiation

   Författare :Cecilia Granéli; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mesenchymal stem cells; Mesenchymal stromal cells; Osteogenic differentiation; Adipogenic differentiation; Bone regeneration; Inflammation; Monocytes; Infection; Bacterial membrane vesicles; Compromised bone healing; Cell surface proteins; CD-markers; Osseointegration; Regenerative medicine;

   Sammanfattning : Mesenchymal stem cells are multipotent stem cells with ability to differentiate into cells of the connective tissue lineage, such as adipocytes, osteoblasts and chondrocytes, both in vitro and in vivo. The main objective of the present thesis was to study different aspects of the osteogenic potential of MSCs. LÄS MER

4. 8. Biology of Human Primary Bone Marrow Mesenchymal Stromal Stem Cells

   Författare :Roshanak Ghazanfari; Avdelningen för molekylär hematologi; []
   Nyckelord :Mesenchymal stem cells;

   Sammanfattning : .... LÄS MER

5. 9. Stem cell function and organ development : analysis of Lhx2 function in hematopoietic stem cells and eye development

   Författare :Lina Dahl; Leif Carlsson; Jan-Ingvar Jönsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Lhx2; hematopoietic system; hematopoietic stem cell; progenitor; embryonic stem cell; embryoid body; eye development; forebrain; eye field transcription factor; Molecular medicine genetics and pathology ; Molekylär medicin genetik och patologi ; molekylär medicin genetik och patologi ; molecular medicine  genetics and pathology ;

   Sammanfattning : When a multicellular organism suffers damages to tissues/organs it heals itself by either substituting the lost cellular matrix by scar formation or by regenerating the lost tissue. Regeneration likely occurs by a recapitulation of the developmental process that formed the organ. LÄS MER

7. 10. Characterisation of human fetal mesenchymal stem cells

   Författare :Cecilia Götherström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Mesenchymal stem cells; fetal stem cell transplantation; intrauterine transplantation; osteogenesis imperfecta; mixed lymphocyte culture; gene array;

   Sammanfattning : Mesenchymal stem cells (MSCs) are present in various tissues of fetal and adult origin. I isolated and expanded MSCs from human fetal 1st trimester livers and observed that they have a shorter cell doubling time compared to adult bone marrow-derived MSCs. LÄS MER