Sökning: "mesangial"

Visar resultat 21 - 25 av 26 avhandlingar innehållade ordet mesangial.

  1. 21. Studies on the inflammatory response in experimental acute pyelonephritis and its importance for the development of renal scarring

    Författare :Adli Khalil; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute pyelonephritis especially in childhood is a serious and globally common bacterial infection. The infecting microorganism is often derived from the patient's own bowel flora and mainly affects the renal parenchyma and pelvis. LÄS MER

  3. 22. Identification of genes and pathways involved in the development and progression of glomerular diseases

    Författare :Dina Dabaghie; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic kidney disease (CKD) affects millions of people worldwide and is characterized by a reduction in glomerular filtration rate and albuminuria resulting in a gradual loss of kidney function. The high prevalence of the disease, along with the limited treatment options available, makes it a major burden to the health care systems around the world. LÄS MER

  4. 23. Renal function and renal histopathology in assessment of course and prognosis in Henoch Schönlein nephritis and IgA nephropathy

    Författare :Stella Edström Halling; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Henoch Schönlein Nephritis (HSN) is a common childhood vasculitis that generally has a self-limiting course but the long-term outcome varies with the clinical picture at onset. Morbidity is high among the most severe cases, and therefore there is a need for intervention. LÄS MER

  5. 24. Fcγ-receptors in systemic autoimmune conditions : lessons from murine mercury-induced autoimmunity

    Författare :Klara Martinsson; Per Hultman; Karin Cederbrant; Johan Rönnelid; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : In this thesis we investigated the role of activating (FcγRI, FcγRIII) and inhibitory (FcγRIIB) Fcγ-receptors on systemic autoimmunity using two mouse strains, DBA/1 (H-2q) and BALB/c mice (H-2d), susceptible to induction of autoimmunity by mercury (Hg).Fc-receptors for IgG (FcγR) link cellular and humoral immune responses, control the balance between activating and inhibitory immune responses and are important in the development of several autoimmune diseases. LÄS MER

  7. 25. Glomerulopathy in normoalbuminuric adolescents with type 1 diabetes : relations between structure, function, metabolic control and ambulatory blood pressure

    Författare :Torun Torbjörnsdotter; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Type 1 diabetes; Adolescents; Metabolic control; Kidney morphology; Basement membrane thickness; Foot process width; Kidney function test; Ambulatory blood pressure monitoring;

    Sammanfattning : An increase in the incidence of type 1 diabetes in childhood has been reported in several countries, especially among the youngest children. Although clinically apparent diabetic vascular disease is rare in children and adolescents, 30-40% are at risk of developing nephropathy during their lifetime which may lead to renal failure. LÄS MER