Sökning: "meningioma"

Visar resultat 11 - 15 av 21 avhandlingar innehållade ordet meningioma.

  1. 11. From a candidate region to gene characterization : analysis of three new genes with respect to meningioma tumorigenesis

    Författare :Myriam Peyrard; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :meningioma; central nervous system; monosomy 22; tumor suppressor gene; ADTBI BAM22 gene; clathrin-coated vesicles; adaptin; assembly protein;

    Sammanfattning : Meningioma is a common and usually benign tumor arising from the meninges covering the central nervous system (CNS). The yearly incidence of symptomatic meningiomas is 1.2 cases per 100 000 individuals but autopsy findings reveal an occurrence ten times higher. LÄS MER

  3. 12. Risk factors, surgical outcome, and quality of life in patients with cranial or spinal meningioma

    Författare :Jenny Pettersson Segerlind; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Meningiomas comprise approximately 30-38% of all cranial tumours and represent the largest group of primary intracranial and intraspinal tumours. Gliomas, of any grade, account for approximately 28% and glioblastomas 15% of the cranial tumours, as comparison. LÄS MER

  4. 13. Factors associated with brain tumor risk : with focus on female sex hormones and allergic conditions

    Författare :Annette Wigertz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Glioma; meningioma; case-control study; contraceptives; hormone replacement therapy; allergy; pregnancy; participation; selection bias;

    Sammanfattning : Every year approximately 1200 people in Sweden are diagnosed with a brain tumor. The two main histological types of brain tumors, gliomas and meningiomas, differ in terms of their localization, histology, prognosis, and probably etiology. LÄS MER

  5. 14. Characterization of candidate disease genes from human chromosomes 11g13 and 22q

    Författare :Darek Kedra; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Fugu rubripes; 11q13 region; MEN1; menin; GCK; DMPKL; meningioma; clathrin; adaptin; NIPSNAP; synaptogyrin; TOM1; SMARCB1;

    Sammanfattning : Two regions of the human genome, 11q13 and 22q, have been shown to harbor numerous disease-related genes, among them tumor suppressor genes (TSGs). The aim of this project was to construct transcription maps within these chromosomal segments, and thus provide a basis for further analysis of some of the genes for their involvement in disease-related processes. LÄS MER

  7. 15. Molecular studies of the insulin-like growth factor system in the brain : focus on growth, tumorigenesis and trauma

    Författare :Ann-Christin Sandberg Nordqvist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :insulin-like growth factors; insulin-like growth factor binding proteins; brain; mRNA; meningioma; glioma; traumatic brain injury; in situ hybridization; Northern blothybridization;

    Sammanfattning : Insulin-like growth factor (IGF) 1 and -2 are synthesized by most tissues of the body and function as autocrine or paracrine agents in a tissue-specific manner. mRNA for IGF-1 and -2, as well as the IGF-binding proteins, are synthesized locally in various regions of the brain. LÄS MER