Sökning: "membrane stabilizer"

Visar resultat 1 - 5 av 8 avhandlingar innehållade orden membrane stabilizer.

  1. 1. Effects of Ubiquinone-10 on the Stability and Mechanical Properties of Lipid Membranes

    Författare :Emma K. Eriksson; Katarina Edwards; Victor Agmo Hernández; Emma Sparr; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ubiquinone-10; lipid bilayers; membrane stabilizer; liposome permeability; osmotic shock; cuvettes; solanesol; Chemistry with specialization in Physical Chemistry; Kemi med inriktning mot fysikalisk kemi;

    Sammanfattning : Ubiquinones are a group of fat-soluble molecules present in many biological membranes. The most abundant version in humans, ubiquinone-10 (Q10), plays an important role in the mitochondrial respiration chain and also functions as a powerful antioxidant. Accumulating evidence suggests that Q10 also could have other functions in the membrane. LÄS MER

  3. 2. Lipid-based liquid crystals as drug delivery vehicles for antimicrobial peptides

    Författare :Lukas Boge; Martin Andersson; Lovisa Ringstad; RISE; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Liquid crystals; liquid crystalline nanoparticles; cubosome; hexosome; phase behavior; antimicrobial peptide; AMP; glycerol monooleate; proteolysis; antimicrobial effect; antimicrobial resistance; bacterial membrane; membrane interaction; infection; topical delivery; pulmonary delivery;

    Sammanfattning : The development of antimicrobial resistance is a great challenge within health sectors worldwide. Thus, demand for new, efficient treatments is urgent in order to treat various bacterial infections. Antimicrobial peptides (AMPs) are a group of antibiotics that have gained more and more attraction in the past decade. LÄS MER

  4. 3. Structural studies of HDL and applications of EM on membrane proteins

    Författare :Lin Zhu; Hans Hebert; Caroline Jegerschöld; Catherine Vénien-Bryan; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; high density lipoprotein; rHDL; apoA-I; transmission electron microscopy; membrane protein; nanodisc; Salipro; transporter; Technology and Health; Teknik och hälsa;

    Sammanfattning : A large number of proteins interact with biological membranes, either integrated in the membrane (PepTSo2), embedded on a membrane surface (5-lipoxygenase) or encircling a cutout of lipid bilayer (apolipoprotein1 (apoA-I). They function as transporters, receptors or biocatalysts in cellular processes like inflammation or cholesterol transport which are touched upon here. LÄS MER

  5. 4. Templating and self-assembly of biomimetic materials

    Författare :Christian Mille; Lennart Bergström; Mika Linden; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; biomimetic; biotemplating; self-assembly; triply periodic minimal surfaces; the gyroid; photonic crystals; band gap; structural color; chirality; butterflies; membrane proteins; lipid bilayers; sol-gel; mesostructured; polyhedral nanofoams; Materials Chemistry; materialkemi;

    Sammanfattning : This thesis focuses on the use of biomolecular assemblies for creating materials with novel properties. Several aspects of biomimetic materials have been investigated, from fundamental studies on membrane shaping molecules to the integration of biomolecules with inorganic materials. LÄS MER

  7. 5. Caveolae associated proteins and how they effect caveolae dynamics

    Författare :Björn Morén; Richard Lundmark; Volker Haucke; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Caveolae; caveolin; EHD2; cavin; microdomain; microscopy; TIRF; AFM; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Caveolae are a type of invaginated membrane domain that has been shown to be involved in several disease states, including lipodystrophy, muscular dystrophies and cancer. Several of these diseases are caused by the lack of caveolae or caveolae-related signaling deficiencies in the tissues in which the caveolar domain are abundant such as lung, adipose, muscle and their related endothelial cells. LÄS MER