Sökning: "membrane receptors"

Visar resultat 11 - 15 av 400 avhandlingar innehållade orden membrane receptors.

  1. 11. Basement membrane collagens in pancreatic cancer : novel stroma-derived tumor markers and regulators of cancer cell growth

    Författare :Daniel Öhlund; Malin Sund; Peter Naredi; Matthias Löhr; Umeå universitet; []
    Nyckelord :Pancreatic cancer; tumor marker; basement membrane; type IV collagen; type XVIII collagen; matrix metalloproteinase; integrin; autocrine loop; tumor stroma; kirurgi; Surgery;

    Sammanfattning : Background: Among the common malignancies, pancreatic cancer has the shortest long-term survival. The aggressive, rapid, and infiltrative growth pattern of pancreatic cancer, together with the lack of specific symptoms, often leads to late diagnosis. LÄS MER

  3. 12. Probing and elucidating the dynamics of virus-membrane interaction via plasma membrane mimics

    Författare :Konrad Thorsteinsson; Marta Bally; Hudson Pace; Gisa Gerold; Susan Daniel; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plasma membrane; supported lipid bilayer; binding kinetics; equilibrium fluctuation analysis; TIRF; FRET; norovirus; HSV; SARS-CoV-2; histo-blood group antigens; ApoE; heparan sulfate; mikrobiologi; Microbiology;

    Sammanfattning : Virus infection is initiated by the attachment of a virion to a susceptible cell’s plasma membrane, in a highly dynamic and well-orchestrated process that encompasses various steps and engages numerous viral and cellular factors. These dynamic steps may include initial non-specific binding to ubiquitous cell-membrane ligands, diffusion across the membrane to a suitable entry site and virus engagement with various receptors and co-receptors on the cell surface. LÄS MER

  4. 13. Applications of hydrodynamic forces for membrane chromatography

    Författare :Björn Johansson Fast; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Membrane chromatography; FRAP; Protein accumulation; Supported lipid bilayer; Microfluidics; SEEC; Diffusion; Hydrodynamic forces; Label-free;

    Sammanfattning : Membrane proteins are proteins that reside in the cell membrane. Due to their position in the cell membrane, the barrier between the cell interior and exterior, they are vital to cell signaling. Moreover, the presence of membrane proteins in the cell's signaling pathways make membrane proteins important drug targets. LÄS MER

  5. 14. Dynorphin A – Interactions with receptors and the membrane bilayer

    Författare :Johannes Björnerås; Lena Mäler; Astrid Gräslund; Göran Widmalm; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biophysics; biofysik; Biochemistry; biokemi;

    Sammanfattning : The work presented in this thesis concerns the dynorphin neuropeptides, and dynorphin A (DynA) in particular. DynA belongs to the wider class of typical opioid peptides that, together with the opioid receptors, a four-membered family of GPCR membrane proteins, form the opioid system. LÄS MER

  7. 15. C. elegans PAQR-2 ‒ A Regulator of Membrane Homeostasis

    Författare :Emma Svensk; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PAQR; LRRIG; glucose; membrane fluidity; desaturase; homeoviscous adaptation;

    Sammanfattning : The progestin and adipoQ receptor (PAQR) protein family is characterized by a 7-transmembrane domain, and a topology reversed that of G-protein coupled receptors, i.e. the N-terminus resides in the cytoplasm. LÄS MER