Sökning: "membrane microdomains"
Visar resultat 1 - 5 av 17 avhandlingar innehållade orden membrane microdomains.
Sammanfattning : Caveolae are invaginated, dynamic microdomains in the plasma membrane and believed to be involved in receptor-mediated uptake of small molecules (potocytosis) and in signal transduction. A phosphatidylinositol glycan, a precursor of potential insulin second messengers, has been found to be enriched in the caveolae-fraction of adipocyte plasma membranes (Parpal et al. LÄS MER
Sammanfattning : Insulin secretion from β-cells is essential for glucose homeostasis and is often dysregulated in diabetes. Intracellular Ca2+ and membrane lipids cooperate to control insulin secretion with high spatial and temporal precision. LÄS MER
Sammanfattning : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. LÄS MER
4. VPU-Mediated Intracellular Targeting of HIV-1 Core Protein Precursor PR55GAG and Association of PR55GAG with Lipid Microdomains
Sammanfattning : HIV-1 has been suggested to use lipid rafts for assembly and budding. Lipid rafts can be separated from the bulk membranes by extraction with non-ionic detergents, such as Triton X-100 at cold, followed by a density gradient centrifugation. LÄS MER
5. Studies on interactions of norovirus capsid protein with fucosylated glycans and galactosylceramide as soluble and membrane bound ligands
Sammanfattning : Noroviruses (NVs) are among the most common viral pathogens which target the gastrointestinal (GI) tract and cause severe diarrhea, vomiting and episodes of abdominal cramps with fever. Millions of people around the world get infected with NVs annually, of which 200,000 cases are estimated to be fatal. LÄS MER