Sökning: "medicinska fakulteten lunds universitet"
Visar resultat 1 - 5 av 32 avhandlingar innehållade orden medicinska fakulteten lunds universitet.
1. Interactions between Streptococcus pyogenes and the Human Immune System
Sammanfattning : Streptococcus pyogenes is a common human pathogen causing mild infections such as tonsillitis and pharyngitis, but is also the cause of life-threatening conditions. To be able to infect the human host, S. pyogenes express different virulence factors. The surface-expressed M protein is a major virulence factor of S. LÄS MER
2. Antigen presenting cells in autoimmune diabetes: phenotype, function and modulation by Linomide
Sammanfattning : The aim of this thesis was to better understand the role of antigen presenting cells (APC) in the development of diabetes in the nonobese diabetic (NOD) mouse. We have shown that DC and Mphi that infiltrate the islets of Langerhans produce tumour necrosis factor-a (TNF-a), a cytokine known to contribute to the pathogenesis in the early stages of diabetes development. LÄS MER
3. Basement membrane components in the chondrocyte extracellular matrix
Sammanfattning : The extracellular matrix (ECM) is a network of macromolecules which, together with cells, forms the various tissues of all metazoan organisms. Cartilage, in contrast to most other tissues, contains relatively few cells in proportion to the volume occupied by ECM. LÄS MER
4. Staphylococcal enterotoxin H - structure and function of a superantigen
Sammanfattning : The aim of this thesis was to characterise the biological functions of the superantigen staphylococcal enterotoxin H (SEH). Superantigens are highly immunostimulatory proteins, which crosslink T cells and antigen presenting cells (APCs). LÄS MER
5. Nitric oxide in central nervous structures associated with water balance and micturition
Sammanfattning : The role of nitric oxide (NO) in the central control of water balance and micturition has not yet been established. In the present thesis, where female rats were used, neuronal NO synthase (nNOS) distribution was studied in structures of the central nervous system known to be associated with the above mentioned control. LÄS MER