Sökning: "medicinsk cellbiologi"

Visar resultat 21 - 25 av 363 avhandlingar innehållade orden medicinsk cellbiologi.

  1. 21. In vitro toxicity testing using human pluripotent stem cell derivatives

    Författare :Gustav Holmgren; Anders Lindahl; Jane Synnergren; Peter Sartipy; Chris Denning; Sahlgrenska Academy at University of Gothenburg; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; toxicity testing; human pluripotent stem cells; cardiomyocytes; hepatocytes; microarray; quantitative proteomics; bioinformatics; transcriptomics; microRNA; Medical sciences; Medicin; Bioinformatik; Bioinformatics;

    Sammanfattning : .... LÄS MER

  3. 22. Insulin Signalling in Human Adipocytes and its Interplay with beta-Adrenergic Control of Lipolysis

    Författare :Cecilia Karlsson; Peter Strålfors; Maria V Turkina; Jan Eriksson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The prevalence of obesity has over the last 40 years nearly tripled and obesity is one of the major risk factors of developing type 2 diabetes. Type 2 diabetes was formerly called adultonset diabetes but today, probably due to the rise in childhood obesity, it is also seen in children and adolescents. LÄS MER

  4. 23. Active cellular forces in variable mechanical microenvironments

    Författare :Adele Khavari; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Traction force; Gradient substrate; Alginate 3D culture; Durotaxis; mechanics;

    Sammanfattning : Our bodies are immensely complex structures, with various systems, organs, and processes that are not only biochemically driven, but strongly dependent on physical mechanics.  At the heart of all these processes are cells, which must generate forces to adhere, spread, differentiate, grow, and move. LÄS MER

  5. 24. Constraint-based modeling of metabolism - interpreting predictions of growth and ATP synthesis in human and yeast

    Författare :Avlant Nilsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; the Crabtree effect; enzyme-constraints; stunting; cellular economy; the Warburg effect; uncoupling; tumor; flux balance analysis; lactate threshold; metabolite depletion;

    Sammanfattning : Growth is the primary objective of the cell. Diseases arise when cells diverge from a healthy growth-pattern. An increased understanding of cellular growth may thus be translated into improved human health. The cell requires materials and free energy (in the form of ATP) in order to grow, metabolism supplies the cell with this. LÄS MER

  7. 25. Characterization of artificial and biological lipid vesicles using TIRF and SPR

    Författare :Thomas Olsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; membrane permeability; chromaffin vesicle; fluorescence; total internal reflection TIRF microscopy; surface plasmon resonance SPR ; vesicle; osmotic shock; cell membrane; liposome; nanoparticle tracking analysis NTA ; large dense core vesicles LDCVs ;

    Sammanfattning : Synthetic lipid vesicles serve as important mimics of cells and the natural membranes that they are enclosed by. As such they are frequently used as simplified models of the highly complex cell membrane to aid in-depth physicochemical and biological characterization of this essential biological structure. LÄS MER