Sökning: "medicinsk biokemi"

Visar resultat 16 - 20 av 428 avhandlingar innehållade orden medicinsk biokemi.

  1. 16. Extracellular matrix as a regulator of cell behavior : Biological effects of hyaluronan biosynthesis and catabolism

    Författare :Mehdi Rahmanian; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Hyaluronan; hyaluronidase; CD44; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Extracellular matrix surrounding cells is an important regulator of cellular functions. Hyaluronan (HA) is a glycosaminoglyean and a constituent component of the extracellular matrix in all tissues. It is synthesized by hyaluronan syntheses (HAS) at the inner surface of cell membrane and degraded by hyaluronidases to small fragments. LÄS MER

  3. 17. Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides

    Författare :Jianhui Rong; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; heparin; heparan sulphate; biosynthesis; 2-O-sulphotransferase; neo-glycosaminoglycan; conjugation; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Heparin and heparan sulphate (HS) are structurally related polysaccharides influencing various biological processes. The biological functions of heparin/HS largely depend on interactions between the negatively charged polysaccharide chains and a variety of proteins. LÄS MER

  4. 18. Characterisation of integrin splice variants and the interaction between integrins and the urokinase receptor

    Författare :Gunbjørg Svineng; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; integrin β1; alternative splicing; Alu element; urokinase receptor; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Integrins are a family of receptors involved in adhesion to extracellular matrix proteins and in cell-cell contacts. Each integrin consists of one a and one β subunit. Our main interest has been the β1 subunit and its splice variants. LÄS MER

  5. 19. Intracellular processing of pre-a-inhibitor

    Författare :Maria Thuveson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; pre-alpha-inhibitor; heavy chain 3; bikunin; intracellular processing; Biokemi; Biochemistry; Biokemi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Pre-α-inhibitor (PαI) is a plasma protein consisting of a 25 and a 75 kDa polypeptide: bikunin and heavy chain 3 (H3), respectively. Both these polypeptides are made by hepatocytes and while passing through the Golgi complex, bikunin, which carries a chondroitin sulfate chain, becomes covalently linked to the C-terminal amino acid residue of H3 via its polysaccharide. LÄS MER

  7. 20. Neural Stem and Progenitor Cells as a Tool for Tissue Regeneration

    Författare :Ulrika Wallenquist; Karin Forsberg Nilsson; Lars Hillered; Karin Holmqvist; Anders Lewén; Johan Bengzon; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; traumatic brain injury; neural stem cells; transplantation; CNS; PNS; progenitor cells; inflammation; CCI; Biochemistry; Biokemi; Neurosurgery; neurokirurgi; Medical Biochemistry; medicinsk biokemi;

    Sammanfattning : Neural stem and progenitor cells (NSPC) can differentiate to neurons and glial cells. NSPC are easily propagated in vitro and are therefore an attractive tool for tissue regeneration. Traumatic brain injury (TBI) is a common cause for death and disabilities. A fundamental problem following TBI is tissue loss. LÄS MER