Sökning: "mechanistic studies"

Visar resultat 1 - 5 av 377 avhandlingar innehållade orden mechanistic studies.

  1. 1. Cardiovascular effects of diesel exhaust : mechanistic and interventional studies

    Författare :Magnus Lundbäck; Anders Blomberg; Benoit Nemery; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; air pollution; diesel exhaust; nitrogen dioxide; endothelin-1; cardiovascular effects; exhaust particle trap; Lung diseases; Lungsjukdomar; lungmedicin; Lung Medicine;

    Sammanfattning : Background: Air pollution is associated with negative health effects. Exposure to combustion-derived particulate matter (PM) air pollution has been related to increased incidence of cardiovascular and respiratory morbidity and mortality, specifically in susceptible populations. Ambient particles, with a diameter of less than 2. LÄS MER

  2. 2. Ru-Based Water Oxidation Catalysts : Development and Mechanistic Studies

    Författare :Andrey Shatskiy; Björn Åkermark; Martin Albrecht; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; ruthenium; catalysis; water oxidation; artificial photosynthesis; Organic Chemistry; organisk kemi;

    Sammanfattning : Oxidation of water constitutes one of the most challenging processes in artificial photosynthesis, which aims at storing solar energy in the form of chemical bonds of high-energy fuels. To facilitate this process, efficient and durable water oxidation catalysts have to be developed and integrated into the complete photosynthetic cells. LÄS MER

  3. 3. Organocatalytic Acylation for the Kinetic Resolution of Secondary Aryl Alcohols : Synthetic Applications and Mechanistic Studies

    Författare :Laura Mesas Sánchez; Peter Dinér; Pavel Kočovský; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; kinetic resolution; organocatalysis; secondary alcohols; reaction progress kinetic analysis; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : The research described in this thesis focuses on the catalytic acylative kinetic resolution (KR) of aromatic secondary alcohols, using a planar-chiral 4-(dimethylamino)pyridine (DMAP) organocatalyst.In the first part of this thesis, the substrate scope of the above mentioned process was expanded to aromatic secondary alcohols that contain an extra functional group in the alkyl moiety, such as 1,2-azido alcohols, 2-hydroxy-2-aryl-ethylphosphonates and 2-hydroxy-2-aryl esters. LÄS MER

  4. 4. Catalytic Processes Mediated by Metal−Organic Frameworks : Reactivity and Mechanistic Studies

    Författare :Vlad Pascanu; Belén Martín-Matute; Seth Cohen; Stockholms universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

    Sammanfattning : The present thesis describes the development of heterogeneous catalytic methodologies using metal−organic frameworks (MOFs) as porous matrices for supporting transition metal catalysts. A wide spectrum of chemical reactions is covered. LÄS MER

  5. 5. Synthetic studies on naphthoxylosides - labeled compounds and mechanistic studies on acetals

    Författare :Richard Johnsson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Fluorescent xylosides; Carbohydrates; Naphthoxylosides; Cancer; Mechanistic studies; Radioactive xylosides; Acetals;

    Sammanfattning : Labeled analogs to an antiproliferative naphthoxyloside have been synthesized and evaluated. Our investigations have shown that the fluorescently labeled analogs are poor structural analogs, and the physical and biological properties are altered to a large extent. LÄS MER