Sökning: "mechanical properties of DNA"

Visar resultat 1 - 5 av 16 avhandlingar innehållade orden mechanical properties of DNA.

  1. 1. Concatemerization of Synthetic Oligonucleotides

    Författare :Lu Sun; [2014]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; gel electrophoresis; DNA-binding; QCM-D; DNA concatemer; hybridization; DNA formation; self-assembly;

    Sammanfattning : DNA nanotechnology has become an important research field because of its advantages in high predictability and accuracy of base-paring recognition. For example, the DNA concatemer, one of the simplest DNA constructs in shape, has been used to enhance signals in biosensing. LÄS MER

  2. 2. Overstretching short DNA – Single-molecule force spectroscopy studies

    Författare :Niklas Bosaeus; [2013]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; DNA stretching; mechanical properties of DNA; single molecule; optical tweezers; DNA structure;

    Sammanfattning : Structural deformation of DNA has a central role in many biological processes. It occurs, for example, during replication, transcription, and regulation of the activity of the genome. To understand these fundamental processes it is necessary to have a detailed knowledge of the mechanical properties of DNA. LÄS MER

  3. 3. Periodontal implications of Salvadora persica L

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Dental Medicine

    Författare :Reham A. Al-Babtain; Karolinska Institutet.; Karolinska Institutet.; [2018]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Periodontal disease is a major public health problem throughout the world and is the most common cause of tooth loss in adults. For periodontitis to develop, specific gram-negative, anaerobic bacteria must predominate in the subgingival microflora, but simple the presence of these bacteria is insufficient to cause periodontal disease as disease progression involves a complex, sequential relationship between infection, inflammation and tissue destruction. LÄS MER

  4. 4. Human pluripotent stem cells : effects of handling and microenvironment

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Neuroscience

    Författare :Frida Holm; Karolinska Institutet.; Karolinska Institutet.; [2012]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Pluripotent stem cells hold great promise in regenerative medicine and drug development due to their developmental potential towards multiple lineages. However, there are still hurdles to overcome before these cells are safe enough for clinical use even though attempts have already been initiated. LÄS MER

  5. 5. Theory of van der Waals bonding: from bulk materials to biomolecules

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Neuroscience

    Författare :Elisa Londero; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; alkanes; extended systems; DNA; band structure; van der Waals Density Functional vdW-DF ; exchange functionals; Density Functional Theory; non-local correlation; layered oxides;

    Sammanfattning : Sparse matter is abundant in Nature.It encompasses systems characterized by an intrinsic low density of electrons in sizeable regions, where the van der Waals forces contribute considerably to cohesion.Given the length scale of the problem, a prediction of these materials requires appropriate tools within a quantum-mechanical framework. LÄS MER