Sökning: "mecA gene"

Hittade 5 avhandlingar innehållade orden mecA gene.

  1. 1. Development of an Ultrasensitive Capacitive DNA-sensor: A promising tool towards microbial diagnostics

    Författare :Ally Mahadhy; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Capacitive DNA-sensor; Enterobacteriaceae; mecA gene; Methicillin resistance; automated sequential injection analysis; sandwichhybridization; elevated temperature; polytyramine;

    Sammanfattning : Fast and sensitive detection of pathogenic microbial cells is a highly important task in medical diagnostics, environmental analysis and evaluation of food safety. Accordingly, the idea of microorganism identification by the recognition of specific DNA sequence using electrochemical technique is one of the leading researches in the development of diagnostic devices. LÄS MER

  3. 2. Species specific susceptibility testing for ß-lactam antibiotics. With special reference to staphylococci

    Författare :Ann Cathrine Petersson; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; bakteriologi; mycology; Mikrobiologi; virology; bacteriology; beta-lactamase; staphylococcus; methicillin resistance; Microbiology; mecA susceptibility testing; virologi; mykologi;

    Sammanfattning : The main objective of this thesis was to identify methods for the detection of ß-lactam resistance in staphylococci, bacteria often causing nosocomial infections. Detection of ß-lactam resistance in these species is difficult due to strong regulation of genes encoding for the two main resistance mechanisms, ß-lactamase production and the penicillin-binding protein (PBP) 2?. LÄS MER

  4. 3. Studies on two bacterial resistance mechanisms to β-lactam antibiotics : extended spectrum β-lactamases in Klebsiella oxytoca and methicillin resistance in staphylococci

    Författare :Shang Wei Wu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Eleven clinical isolates of Klebsiella oxytoca from Stockholm hospitals were found to be resistant to aztreonam and cefuroxime (MIC > 16 mg/L). The resistance was caused by a ß-lactamase with pI 5.25 and designated KH. Assay of the substrate profiles revealed that the KH ß-lactarnase was similar to the chromosomally encoded OXY-2 ß-lactamase. LÄS MER

  5. 4. Antibiotic Resistance in Wastewater : Methicillin-resistant Staphylococcus aureus (MRSA)and antibiotic resistance genes

    Författare :Stefan Börjesson; Per-Eric Lindgren; Johanna Ericson Sollid; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MRSA; SCCmec; spa typing; Staphylococcus aureus; methicillin; B-lactam; aminoglycoside; tetracycline; antibiotic; wastewater; wastewater treatment plant; Microbiology; Mikrobiologi;

    Sammanfattning : A large part of the antibiotics consumed ends up in wastewater, and in the wastewater the antibiotics may exert selective pressure for or maintain resistance among microorganisms. Antibiotic resistant bacteria and genes encoding antibiotic resistance are commonly detected in wastewater, often at higher rates and concentrations compared to surface water. LÄS MER

  7. 5. Epidemiological and molecular biological studies of multi-resistant methicillin-susceptible Staphylococcus aureus

    Författare :Maria Lindqvist; Anita Hällgren; Barbro Isaksson; Lennart E. Nilsson; Christina Åhrén; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : Antibiotic resistance is increasingly recognised as a major problem and threat. During the last decades Gram-positive bacteria in general, and methicillin-resistant Staphylococcus aureus (MRSA) in particular, have been in focus both concerning matters of antibiotic resistance and as pathogens causing health care-associated (nosocomial) infections. LÄS MER