Sökning: "mcl-1"

Visar resultat 11 - 12 av 12 avhandlingar innehållade ordet mcl-1.

  1. 11. Molecular characterization of apoptosis in B-cell chronic lymphocytic leukemia

    Författare :Anna Olsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :B-CLL; apoptosis; TRAIL; FLIP; Bmf; Bfl-1;

    Sammanfattning : B-cell chronic lymphocytic leukemia (B-CLL), characterized by an accumulation of monclonal B cells, is the most common adult leukemia in the Western world. Defective apoptosis is considered to contribute to cell accumulation, disease progression and resistance to therapy in BCLL. LÄS MER

  3. 12. The impact of Bcl-2 family members on mast cell survival and apoptosis

    Författare :Maria Ekoff; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Mast cells are long-lived effector cells of the immune system perhaps best known for their involvement in allergic diseases. There are several acute and chronic inflammations where mast cell accumulation, activation and release of mediators are important for the initiation and perpetuation of the inflammation. LÄS MER