Sökning: "mbn-2"
Hittade 4 avhandlingar innehållade ordet mbn-2.
1. Interaction Between Drosophila melanogaster mbn-2 Cells and Bacteria
Sammanfattning : Innate immunity relies on a repertoire of germline-encoded non-rearranging pattern recognition receptors that bind to invariant microbial surface molecules. This event initiates a number of signal transduction cascades that lead to humoral and cellular defense responses like synthesis of antimicrobial peptides, phagocytosis and coagulation – mechanisms that efficiently fight infectious microorganisms and have been evolutionary conserved to exist in parallel with the antibody-based adaptive immunity found in vertebrates. LÄS MER
2. Peptidoglycan recognition proteins in Drosophila melanogaster
Sammanfattning : The fruit fly Drosophila melanogaster is an excellent model organism to study the innate immune response, because insects and mammals share conserved features regarding the recognition and destruction of microorganisms and Drosophila is easily accessible to genetic manipulation. In my present study, I identified a new family of pattern recognition molecules for bacterial peptidoglycan in Drosophila, the Peptidoglycan Recognition Proteins (PGRP). LÄS MER
3. Involvement of Rel and GATA transcription factors in the regulation of antimicrobial peptide gene expression in Drosophila melanogaster
Sammanfattning : Insects posses a powerful immune system related to the innate immune reactions present in vertebrates. When insects are infected by bacteria or other microorganisms, a vast production of different antimicrobial peptides is activated. The expression of antimicrobial peptides is regulated at the level of transcription. LÄS MER
4. A molecular characterization of selected cecropins and cysteine proteinases in Drosophila
Sammanfattning : Insects that have been infected with bacteria produce antibacterial peptides. Among the most potent antibacterial peptides in Drosophila are the cecropins. This work describes the cloning and expression studies of the CecC gene, which completes the picture of the cecropin locus in Drosophila melanogaster. LÄS MER