Sökning: "maximum tolerable dose MTD"

Hittade 3 avhandlingar innehållade orden maximum tolerable dose MTD.

1. 1. Safety limit estimation for cataract induced by ultraviolet radiation

   Författare :Xiuqin Dong; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ultraviolet radiation UVR ; Sprague-Dawley rat; cataract; light scattering; doseresponse function; maximum acceptable dose MAD ; maximum tolerable dose MTD ; in vivo; in vitro; age.;

   Sammanfattning : Background: Ultraviolet radiation (UVR) is considered one of the major risk factors for agerelated cataract. UVR-induced cataract follows a continuous dose-response function. LÄS MER

3. 2. Cataract from ultraviolet radiation in the mouse

   Författare :Linda Maren Meyer; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Lens; cataract; ultraviolet radiation; oxidative stress; mouse; light scattering;

   Sammanfattning : Cataract is defined as an opacification of the crystalline lens that results in visual impairment, Cataract is the number one cause of blindness in the world and there are currently no strategies to prevent it. Extraction of cataractogenous lenses is the most commonly performed surgical intervention in industrialized countries. LÄS MER

4. 3. Alpha-radioimmunotherapy with At-211: Evaluations and imaging on normal tissues and tumors

   Författare :Tom Bäck; Göteborgs universitet; []
   Nyckelord :radioimmunotherapy; astatine; RBE; renal function; GFR; imaging; targeted radiotherapy; alpha-RIT;

   Sammanfattning : Alpha-radioimmunotherapy (alpha-RIT) is an internal conformal radiotherapy at the cellular level using alpha-particle emitting radionuclides. Alpha-particles have a very short range in tissues (... LÄS MER