Sökning: "maximum acceptable dose MAD"

Hittade 2 avhandlingar innehållade orden maximum acceptable dose MAD.

1. 1. Safety limit estimation for cataract induced by ultraviolet radiation

   Författare :Xiuqin Dong; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Ultraviolet radiation UVR ; Sprague-Dawley rat; cataract; light scattering; doseresponse function; maximum acceptable dose MAD ; maximum tolerable dose MTD ; in vivo; in vitro; age.;

   Sammanfattning : Background: Ultraviolet radiation (UVR) is considered one of the major risk factors for agerelated cataract. UVR-induced cataract follows a continuous dose-response function. LÄS MER

3. 2. Development and repair of cataract induced by ultraviolet radiation

   Författare :Ralph Michael; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :ultraviolet radiation; cataract; forward light scattering; lens ultrastructure; refractive index; dose-response; repeated exposure; apoptosis; in vivo; rat;

   Sammanfattning : Background: Several epidemiological investigations show a correlation between cataract development and the dose of ultraviolet radiation (UVR) received. It is experimentally well established that exposure of animal eyes to UVR induces cataract. Most cataracts develop as a gradual increase in lens opacity. LÄS MER