Sökning: "mats ohlin"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden mats ohlin.

  1. 1. Human monoclonal antibody technology. A tool to investigate human antibody repertoires

    Författare :Mats Ohlin; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The development of technologies to generate cell lines producing monoclonal antibodies of human origin has a great impact on the ability to study repertoires of specificities in the humoral immune response. Furthermore, it permits the generation of reagents which may be valuable for diagnostic and therapeutic applications and which lack some of the disadvantages of similar murine antibodies. LÄS MER

  3. 2. Aspects on early diagnosis of neonatal sepsis

    Författare :Andreas Ohlin; Jens Schollin; Maria Björkqvist; Mats Blennow; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICINE; MEDICIN; Paediatric medicine; Pediatrisk medicin; Pediatrik; Pediatrics;

    Sammanfattning : This thesis presents four studies, all designed to improve the problematic diagnostic situation concerning infants with suspected sepsis. Study I included 401 neonates with suspected sepsis. LÄS MER

  4. 3. Interaction studies of idiotypic and antiidiotypic antibodies at experimental tumor targeting

    Författare :Ann Erlandsson; Mats Ohlin; Umeå universitet; []
    Nyckelord :anti-idiotypic antibody; clearing; cytokeratin 8; epitope; idiotypic antibody; immunotherapy;

    Sammanfattning : An increasing number of antibodies are being labeled with radionuclides for immunotargeting, but the negative side effects generated on normal tissues by the nuclide remains a significant problem. The clearing of non-tumor-targeted radiolabeled antibodies from the circulation contributes significantly to improved targeting; it has been demonstrated that anti-idiotypic antibodies can be used for this purpose. LÄS MER

  5. 4. Routine procedures in the care of the full-term newborn

    Författare :Miriam Pettersson; Mats H. Eriksson; Andreas Ohlin; Fredrik Ahlsson; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Newborn; pain; neonatal hyperbilirubinemia; home phototherapy; neonatal hip examination; oral sweet solution; pain assessment;

    Sammanfattning : This thesis presents four studies on routine procedures used in the care of the full-term newborn. The overall aim of the thesis was to study the effects of these routines and endeavour to find ways to improve them.Study I, an observational study, included 28 healthy newborns, assessing pain during neonatal hip examination. LÄS MER

  7. 5. Characterization of Antigenic Properties and High Throughput Protein Purification

    Författare :Johanna Steen; Sophia Hober; Mats Ohlin; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; high throughput; protein purification; sample preparation; antigen solubility; immunogenicity; epitope mapping; antigen design; Bioengineering; Bioteknik; SRA - Molecular Bioscience; SRA - Molekylär biovetenskap;

    Sammanfattning : To understand the cellular processes, knowledge of the localization and function of proteins are essential. There are several high throughput ventures examining the human proteome. However, there are some bottlenecks in these ventures. For example the production and expression of soluble proteins for analysis. LÄS MER