Sökning: "mathiesen"

Visar resultat 1 - 5 av 6 avhandlingar innehållade ordet mathiesen.

1. 1. On the antiporter-like subunits of respiratory chain Complex I - implications for the evolution and coupling mechanism of the NADH:quinone oxidoreductase enzyme complex

   Författare :Cecilie Mathiesen; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Metabolism; Biokemi; metabolism; Biochemistry; mrp; electron transport; respiration; membrane protein;

   Sammanfattning : Complex I or NADH:quinone oxidoreductase is the largest enzyme complex, but the least understood energy coupling site in the respiratory chain of mitochondria and bacteria. No high-resolution structural information exists for this enzyme and the molecular mechanism that couples electron transfer and proton pumping is not understood. LÄS MER

3. 2. Late complications after total hip arthroplasty

   Författare :Erik B Mathiesen; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The present study concerns late complications after total hip arthroplasty in relation to implant material, design, and mode of implant fixation. Frictional characteristics in retrieved and new acetabular sockets was studied under dry and lubricated conditions comparing conventional polyethylene sockets with polyacetal sockets from the Christiansen prosthesis. LÄS MER

4. 3. Delayed Cell Death after Traumatic Brain Injury : Role of Reactive Oxygen Species

   Författare :Fredrik Clausen; Lars Hillered; Tiit Mathiesen; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Traumatic Brain Injury; Reactive oxygen species; Fluid percussion injury; Controlled cortical impact; weight drop injury; Extracellular-signal regulated kinase; apoptosis; free radical scavenging; morphology; functional outcome; Neurovetenskap; Neurology; Neurologi;

   Sammanfattning : Traumatic brain injury (TBI) is a leading cause of death and disability TBI survivors often suffer from severe disturbances of cognition, memory and emotions. Improving the treatment is of great importance, but as of yet no specific neuroprotective treatment has been found. LÄS MER

5. 4. The Neurological Wake-up Test in Neurocritical Care

   Författare :Karin Skoglund; Niklas Marklund; Per Enblad; Tiit Mathiesen; Uppsala universitet; []
   Nyckelord :Intracranial pressure; Cerebral perfusion pressure; Propofol sedation; Wake-up test; stress hormones; intracerebral microdialysis; brain tissue oxygenation; jugular venous oxygenation; Neurokirurgi; Neurosurgery;

   Sammanfattning : The neurological wake-up test, NWT, is a clinical monitoring tool that can be used to evaluate the level of consciousness in patients with traumatic brain injury (TBI) and subarachnoid haemorrhage (SAH) during neurocritical care (NCC). Since patients with severe TBI or SAH are often treated with mechanical ventilation and sedation, the NWT requires that the continuous sedation is interrupted. LÄS MER

7. 5. Narrowing the gap between network models and real complex systems

   Författare :Alcides Viamontes Esquivel; Martin Rosvall; Joachim Mathiesen; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; complex systems; network science; community detection; model selection; signficance analysis; ergodicity; fysik; Physics;

   Sammanfattning : Simple network models that focus only on graph topology or, at best, basic interactions are often insufficient to capture all the aspects of a dynamic complex system. In this thesis, I explore those limitations, and some concrete methods of resolving them. LÄS MER