Sökning: "matematik screening"
Visar resultat 1 - 5 av 13 avhandlingar innehållade orden matematik screening.
1. Extreme Value Analysis of Huge Datasets: Tail Estimation Methods in High-Throughput Screening and Bioinformatics
Sammanfattning : This thesis presents results in Extreme Value Theory with applications to High-Throughput Screening and Bioinformatics. The methods described here, however, are applicable to statistical analysis of huge datasets in general. The main results are covered in four papers. LÄS MER
2. Parameter estimation in heterogeneous catalysis
Sammanfattning : The detailed modelling of heterogeneous catalytic systems is challenging due to the unknown nature of new catalytic materials as well as the often required transient nature of the resulting models. Thus, this thesis deals with the methodologies involved in the kinetic modelling of heterogeneous catalysis and in particular NOx reduction systems. LÄS MER
3. Optimisation of Clinical Trials using Bayesian Decision Theory
Sammanfattning : A decision maker confronted with the task of designing a clinical trial has to consider a multitude of aspects. Large trials lead to more evidence,which in turn makes it less likely that harmful decisions are taken when deciding on future treatments for patients. LÄS MER
4. Computational methods for assessing chemical risk : focusing on toxicokinetic modelling in zebrafish (danio rerio)
Sammanfattning : New chemicals are constantly produced and large data gaps exist on hazards of currently used industrial chemicals, stressing the need for rapid, ethically sound and cost-efficient hazard assessment methods. Traditional methods for effect assessment based on animal testing, do not meet these requirements and thus the toxicology field has been moving towards the development of new approach methodologies which include in vitro approaches but also computational methods. LÄS MER
5. Statistical modelling in chemistry - applications to nuclear magnetic resonance and polymerase chain reaction
Sammanfattning : This thesis consists of two parts with the common theme of statistical modelling in chemistry. The first part is concerned with applications in nuclear magnetic resonance (NMR) spectroscopy, while the second part deals with applications in polymerase chain reaction (PCR). LÄS MER
