Sökning: "master"

Visar resultat 11 - 15 av 400 avhandlingar innehållade ordet master.

  1. 11. Downstream effects of master regulators in two brain diseases

    Författare :Sebastian Braun; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Rett syndrome; brain tumor development; gene regulation; neural stem cells; cell of origin; BMI1;

    Sammanfattning : In paper one, we investigated how the pharmacological activation and inhibition of the glucocorticoid system affects lifespan and symptoms in a mouse model for RTT. We performed a long-term drug treatment study with the GR activator corticosterone and the GR inhibitor RU486 under which we measured the lifespan and onset of RTT-like symptoms of male Mecp2-null and female Mecp2 heterozygous mice in comparison to untreated mutant and to treated and untreated wild-type animals. LÄS MER

  3. 12. Cell-matrix interactions : master regulators of cancer cell fate?

    Författare :Sara Göransson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The development and homeostasis of a multicellular organism require fundamental biological processes like cell proliferation, cell differentiation, cell migration, and controlled cell death. The extracellular matrix (ECM) guides many of these functions, via cell-matrix interactions that function as mechanical and biochemical signaling hubs. LÄS MER

  4. 13. Processing Methods for Reaching Full Density Powder Metallurgical Materials

    Författare :Maheswaran Vattur Sundaram; Chalmers tekniska högskola; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; gas atomised powder; water atomised powder; high density powder metallurgical materials; high density; master alloys; liquid phase sintering; sintering; high velocity compaction; hot isostatic pressing; additive manufacturing;

    Sammanfattning : Powder metallurgy (PM) is one of the most cost effective methods for manufacturing structural components with complex shapes. Utilisation of the metal powder to shape the components allows to minimise material waste and increase energy efficiency. LÄS MER

  5. 14. Numerical Methods for Stochastic Modeling of Genes and Proteins

    Författare :Paul Sjöberg; Per Lötstedt; Måns Ehrenberg; Achim Schroll; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; master equation; Fokker-Planck equation; stochastic models; biochemical reaction networks; Scientific Computing; Beräkningsvetenskap;

    Sammanfattning : Stochastic models of biochemical reaction networks are used for understanding the properties of molecular regulatory circuits in living cells. The state of the cell is defined by the number of copies of each molecular species in the model. LÄS MER

  7. 15. The Diversity and Unity of Reactor Noise Theory

    Författare :Zhifeng Kuang; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neutron fluctuations; master equations; correlations; stochastic processes; the Langevin technique; power spectra; reactor noise; covariances;

    Sammanfattning : The study of reactor noise theory concerns questions about cause and effect relationships, and the utilisation of random noise in nuclear reactor systems. The diversity of reactor noise theory arises from the variety of noise sources, the various mathematical treatments applied and the various practical purposes. LÄS MER