Sökning: "masspektrometri"

Visar resultat 16 - 20 av 65 avhandlingar innehållade ordet masspektrometri.

  1. 16. Investigation of Modified Cellulose and Starch via Hydrolysis and Mass Spectrometry

    Författare :Arieh Cohen; Avdelningen för arbets- och miljömedicin; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ESI-MS; Polysaccharides; Hydrolysis; Cellulases; Starch Hydrolases; Enzymatic Degradation; Enzymes; Substituent Distribution; Modified Cellulose; Mass Spectrometry; Modified Starch; Analytical chemistry; Analytisk kemi; HPAEC-PAD;

    Sammanfattning : Starches and celluloses can be chemically modified in order to affect their physiochemical properties. Modification of these carbohydrate polymers entails derivatising their free hydroxyl groups with functional groups. LÄS MER

  3. 17. Development of novel affinity enrichment strategies for clinical applications using selected reaction monitoring

    Författare :Andreas Hober; Mathias Uhlén; Fredrik Edfors; Björn Forsström; Johan Malmström; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; proteomics; mass spectrometry; selected reaction monitoring; absolute quantification; antibody validation; precision medicine; Biotechnology; Bioteknologi;

    Sammanfattning : Proteins are key components of any living organism and an essential part of life itself. They can provide cells with structure and perform life-sustaining intracellular reactions. As organisms grow more complex, this task expands even further. LÄS MER

  4. 18. Methods for protein analysis by capillary electrophoresis and mass spectrometry

    Författare :Joakim Romson; Åsa Emmer; Peter Dinér; Lukas Käll; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; MALDI; Concentration plates; Alkyl ketene dimer; CE-MALDI-MS2; On-target digestion; Automation; Robot; Pieris napi; spermatophore; ESI-MS2; Osteopontin; MALDI; Koncentrationsprovplatta; alkylketenedimer; CE-MALDI-MS2; enzymklyvning på provplatta; Automatisering; Robot; Pieris napi; Spermatofor; ESI-MS2; Osteopontin; Kemi; Chemistry;

    Sammanfattning : Protein analysis is important to understanding biological systems, but sample diversity necessitates a multitude of analysis techniques and methods. Challenges that are addressed include analysis of low abundance samples, fractionation to reduce sample complexity, and automation to reduce time and cost. LÄS MER

  5. 19. Exploring small heat shock protein chaperones by crosslinking mass spectrometry

    Författare :Wietske Lambert; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cross-linking; mass spectrometry; protein-protein interactions; Hsp21; BS3; DTSSP; MALDI-TOF TOF; client protein; substrate; aggregation; unfolded protein; chaperone; Small heat shock protein; crosslinking;

    Sammanfattning : Together with other molecular chaperones, small heat shock proteins are key components of the protein quality control system, which is comprised of several hundred proteins and acts to maintain proteome homeostasis in the cell. Small heat shock proteins bind unfolding proteins at an early stage, to prevent these from further unfolding and aggregating. LÄS MER

  7. 20. A Proteomic Dissection of Breast Cancer - Via Cells and Organelles to Pathways

    Författare :Linn Antberg; Institutionen för immunteknologi; []
    Nyckelord :Proteomics; Mass spectrometry; Breast cancer; DNA repair; Organelle fractionation; Tumour subpopulations;

    Sammanfattning : Breast cancer is the most frequently diagnosed cancer and the leading cause of cancer death in females worldwide. Breast tumours are extremely heterogeneous, and each patient’s disease has different causes, prognosis and appropriate treatments associated with it. LÄS MER