Sökning: "massively"

Visar resultat 1 - 5 av 101 avhandlingar innehållade ordet massively.

  1. 1. Massively parallel analysis of cells and nucleic acids

    Författare :Julia Sandberg; Joakim Lundeberg; Nader Pourmand; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Massively parallel sequencing; 454; Illumina; multiplex amplification; whole genome amplification; single cell; polyguanine; flow-cytometry;

    Sammanfattning : Recent proceedings in biotechnology have enabled completely new avenues in life science research to be explored. By allowing increased parallelization an ever-increasing complexity of cell samples or experiments can be investigated in shorter time and at a lower cost. LÄS MER

  3. 2. Genetic Cartography at Massively Parallel Scale

    Författare :Johan Dahlberg; Ann-Christine Syvänen; Adam Ameur; Michael C. Zody; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; NATURVETENSKAP; NATURAL SCIENCES; Acute Lymphoblastic Leukemia ALL ; RNA-Sequencing; Bioinformatics; Pooling; Whole Genome Sequencing; Medicinsk genetik; Medical Genetics; Bioinformatics; Bioinformatik;

    Sammanfattning : Massively parallel sequencing (MPS) is revolutionizing genomics. In this work we use, refine, and develop new tools for the discipline.MPS has led to the discovery of multiple novel subtypes in Acute Lymphoblastic Leukemia (ALL). In Study I we screen for fusion genes in 134 pediatric ALL patients, including patients without an assigned subtype. LÄS MER

  4. 3. Massively Parallel Sequencing of Gene Fusion-Associated Sarcomas

    Författare :Jakob Hofvander; Avdelningen för klinisk genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sarcomas; Gene fusion; tumor evolution; clonal heterogeneity; RNA-seq; WES; SNP-array;

    Sammanfattning : .... LÄS MER

  5. 4. Characterization of structural chromosomal variants by massively parallel sequencing

    Författare :Jesper Eisfeldt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chromosomal Structural Variation (SV) such as translocations, inversions, deletions, and duplications are rearrangements of one or several DNA molecules. SVs are widespread across the human genome, and each individual carries thousands of SVs of different types and sizes. LÄS MER

  7. 5. Energy-Efficient Computing over Streams with Massively Parallel Architectures

    Författare :Nicolas Melot; Christoph Kessler; Joerg Keller; Krzysztof Kuchcinski; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY;

    Sammanfattning : The rise of many-core processor architectures in the high-performance computing market answers to a constantly growing need of processing power to solve more and more challenging problems such as the ones in computing for big data. Fast computation is more and more limited by the very high power required and the management of the considerable heat produced. LÄS MER