Sökning: "massively parallel sequencing"
Visar resultat 11 - 15 av 36 avhandlingar innehållade orden massively parallel sequencing.
11. Analysis of RNA and DNA sequencing data : Improved bioinformatics applications
Sammanfattning : Massively parallel sequencing has rapidly revolutionized DNA and RNA research. Sample preparations are steadfastly advancing, sequencing costs have plummeted and throughput is ever growing. This progress has resulted in exponential growth in data generation with a corresponding demand for bioinformatic solutions. LÄS MER
12. Characterization of structural chromosomal variants by massively parallel sequencing
Sammanfattning : Chromosomal Structural Variation (SV) such as translocations, inversions, deletions, and duplications are rearrangements of one or several DNA molecules. SVs are widespread across the human genome, and each individual carries thousands of SVs of different types and sizes. LÄS MER
13. Technologies for Single Cell Genome Analysis
Sammanfattning : During the last decade high throughput DNA sequencing of single cells has evolved from an idea to one of the most high profile fields of research. Much of this development has been possible due to the dramatic reduction in costs for massively parallel sequencing. LÄS MER
14. Transcriptomic and taxonomic profiling of periodontitis by massively parallel sequencing
Sammanfattning : Periodontitis is a microbial-induced, chronic inflammatory disease that affects tissue and bone anchoring the teeth, and can ultimately lead to tooth loss. In addition, periodontitis may contribute to systemic diseases, such as cardiovascular disease (CVD), diabetes, rheumatoid arthritis (RA), and inflammatory bowel diseases. LÄS MER
15. Analysis of genetic variations in cancer
Sammanfattning : The aim of this thesis is to apply recently developed technologies for genomic variation analyses, and to ensure quality of the generated information for use in preclinical cancer research.Faster access to a patients’ full genomic sequence for a lower cost makes it possible for end users such as clinicians and physicians to gain a more complete understanding of the disease status of a patient and adjust treatment accordingly. LÄS MER