Sökning: "marijke sachweh"

Hittade 1 avhandling innehållade orden marijke sachweh.

1. 1. Small molecules that affect the p53 pathway and their potential use in the treatment of cancer

   Författare :Marijke Cornelia Christine Sachweh; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The tumor suppressor p53 was identified 35 years ago and has since then been studied extensively, but despite all efforts, no drug or therapy directly involving it has been clinically approved - yet! A lot of potential new drugs are on their way that can reactivate p53 function by various mechanisms. Even a whole new approach called cyclotherapy has been established, during which p53 is activated in normal cells to protect patients from the adverse effects of chemotherapy while tumor cells are still being killed efficiently. LÄS MER