Sökning: "maoa"

Visar resultat 1 - 5 av 12 avhandlingar innehållade ordet maoa.

  1. 1. Predictors of Alcohol Misuse : Role of MAOA Genotype, Methylation, Transcription, and Negative and Positive Environmental factors

    Författare :Megha Bendre; Kent Nilsson; Erika Comasco; Ingrid Nylander; Mia Ericson; Uppsala universitet; []
    Nyckelord :Alcohol; AUD; MAOA; methylation; expression; early-life stress; maltreatment; parent–child relationship; gene–environment interactions.; Medicinsk vetenskap; Medical Science;

    Sammanfattning : Alcohol misuse is a risk factor for alcohol use disorder (AUD). Gene-environment interactions contribute to the risk or resilience for AUD. A functional polymorphism in the promoter of the monoamine oxidase A gene (MAOA-uVNTR), in interaction with negative environment (Eneg), is associated with alcohol misuse and AUD. LÄS MER

  3. 2. Maf transcription factors in beta cell function

    Författare :Elvira Ganic; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Beta cell; MafA; type 2 diabetes; insulin secretion; transcription; monoamine oxidase; MaoA; MaoB; nicotinic receptor subunits; nAChRs;

    Sammanfattning : Diabetes mellitus is metabolic disorder caused by a defect or lack of beta cell-produced insulin that controls blood glucose homeostasis. In addition to glucose, insulin secretion is regulated by the autonomic nervous system (ANS); the neurotransmitter acetylcholine as well as monoamines, such as dopamine, serotonin, melatonin and norepinephrine. LÄS MER

  4. 3. Genetic studies of depressive symptoms

    Författare :Mårten Jansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Depressive Symptoms; Twin; Heritability; Serotonin receptor 2A; Serotonin transporter; MAOA; MAOB; Thrombocyte MAO activity; Linkage Disequilibrium.;

    Sammanfattning : This thesis is focused on depressive symptoms particularly in late fife. Depressive symptoms are associated with serious negative outcomes a greater level of disability and with excess morbidity and mortality. LÄS MER

  5. 4. The Monoamine Oxidase A Gene and Antisocial Outcomes : An Examination of Genetic, Epigenetic, and Environmental Factors

    Författare :David Checknita; Kent W. Nilsson; Lars Westberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Epigenetics; Antisocial; Genotype; Maltreatment;

    Sammanfattning : Background. Antisocial behaviour involves violation of the basic rights of others or social norms or rules. Such behaviours are indexed in diagnoses such as conduct disorder (CD) in adolescence and antisocial personality disorder (ASPD) in adulthood, which are typified by comorbidity with mood, anxiety, and substance misuse disorders. LÄS MER

  7. 5. Depression and Antisocial Behaviour in Adolescents : Influence of Social Status, Shaming, and Gene-Environment Interaction

    Författare :Cecilia Åslund; Kent W Nilsson; Jerzy Leppert; Bengt Starrin; Lars Oreland; Lil Träskman-Bendz; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; adolescent; antisocial behaviour; depression; gene-environment interaction; maltreatment; monoamine oxidase; serotonin; shame; social status; Child and adolescent psychiatry; Barn- och ungdomspsykiatri; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

    Sammanfattning : This thesis investigated (1) social status and shaming experiences in relation to aggressive behaviour and depression, and (2) gene-environment interactions between two genetic polymorphisms related to the serotonergic system – MAOA-VNTR and 5HTTLPR – and experiences of maltreatment in relation to delinquent behaviour and depression among adolescents. The four included studies are based on questionnaire data from the Survey of Adolescent Life in Vestmanland 2006 (SALVe-2006). LÄS MER