Sökning: "mannose"

Visar resultat 6 - 10 av 52 avhandlingar innehållade ordet mannose.

  1. 6. Tales from the Sweet Side of Life : Structure and dynamics of carbohydrate-based systems

    Författare :Alessandro Ruda; Göran Widmalm; Jesús Jiménez Barbero; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; carbohydrates; nuclear magnetic resonance; molecular dynamics; glycans; conformational analysis; structure elucidation; protein-glycan interactions; Organic Chemistry; organisk kemi;

    Sammanfattning : The field of glycomics has experienced significant developments in the last few decades, revealing a profound and elaborate language behind the intrinsic complexity of the glycans structures. This ‘sugar code’ is at the basis of intercellular interaction and recognition. For this language to be understood, its chemical basis must be unveiled. LÄS MER

  3. 7. Synthesis of inositol phosphoglycans and analogues thereof

    Författare :Katinka Ruda; JS Brimacombe; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi; Organic Chemistry; organisk kemi;

    Sammanfattning : This thesis describes the synthesis of inositol phosphoglycans (IPG) corresponding to glycosyl-phosphatidylinositol (GPI) anchors found on the cell surface of the parasite Leishmania. Synthesis of an IPG which is a putative second messenger for insulin, and of analogues thereof is also discussed. LÄS MER

  4. 8. Synthesis of Carbohydrate Mimics and Development of a Carbohydrate Epimerisation Method

    Författare :Clinton Ramstadius; Ian Cumpstey; Robert Madsen; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbohydrate Mimic; Ring-closing Metathesis; Carbohydrate Chemistry; Carbasugar; Aminocarbasugar; Pseudodisaccharide; Glycosidase and Lectin Inhibitors; Organic chemistry; Organisk kemi; organisk kemi; Organic Chemistry;

    Sammanfattning : In this thesis the synthesis of several hydrolytically stable carbohydrate mimics with the potential to function as glycosidase or lectin inhibitors are described. This work is presented in Chapters 2-5. LÄS MER

  5. 9. Synthesis of oligosaccharides related to the capsular polysaccharide of Neisseria meningitidis serotype A

    Författare :Peter Teodorovic; Stefan Oscarson; Mikael Elofsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; Organisk kemi;

    Sammanfattning : In order to find suitable stable vaccine candidates against Neisseria meningitidis group A, several structures related to the capsular polysaccharide have been synthesised. The first part of the thesis describes the synthesis of C-phosphonate analogues starting from glucose. LÄS MER

  7. 10. Pichia pastoris as a platform for the production of therapeutic glycoproteins

    Författare :Magnus Sjöblom; Luleå tekniska universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biokemisk processteknik; Biochemical Process Engineering;

    Sammanfattning : Recombinant protein therapeutics is a growing market within the human medical biotechnology industry. The majority of all approved biopharmaceuticals are protein based and includes for example blood factors, anticoagulants, hormones, vaccine and monoclonal antibodies. LÄS MER