Sökning: "mannan-binding lectin MBL"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden mannan-binding lectin MBL.
- Detta är en avhandling från Lund University
Sammanfattning : In cystic fibrosis (CF) colonization of the airways with Pseudomonas aeruginosa is a major cause of deterioration and death. Host defence fails to clear the invading bacteria, which results in a chronic destructive inflammatory process. LÄS MER
2. Recognition molecules of the complement system: C1q and mannan-binding lectin in autoimmunity and immune defenceDetta är en avhandling från Department of Laboratory Medicine, Lund University
Sammanfattning : The C1 subcomponent C1q and the mannan-binding lectin (MBL) are recognition proteins of the complement system, and have similar structure. C1q binds to IgG and IgM and activates the classical pathway. MBL binds to carbohydrate structures and activates the lectin pathway. LÄS MER
- Detta är en avhandling från Department of Laboratory Medicine, Lund University
Sammanfattning : The complement system is critically involved in defence against bacterial infection. C2 deficiency is, apart from mannan-binding lectin (MBL) deficiency, the most common homozygous complement deficiency among Caucasians. LÄS MER
4. Studies on hereditary C2 deficiency: Frequent occurrence of severe infections, atherosclerosis and rheumatological manifestationsDetta är en avhandling från Department of Medical Microbiology, Lund University
Sammanfattning : The complement system is a part of the innate immunity and is essential in the defence against microorganisms. Hereditary C2 deficiency (C2D) is one of the most common complement deficiency states with an estimated prevalence of 1:20,000 in persons of Western descent. LÄS MER
5. Complement aberrations and autoantibodies to complement proteins in relation to disease mechanismsDetta är en avhandling från Department of Laboratory Medicine, Lund University
Sammanfattning : The complement system, a part of the innate immune system with several links to the adaptive immune system, plays an important role in the pathogenesis of many diseases. The purpose of this thesis was to document and clarify some of these mechanisms. The thesis is based on four papers (I-IV). LÄS MER