Sökning: "mammalian cells"

Visar resultat 16 - 20 av 493 avhandlingar innehållade orden mammalian cells.

  1. 16. DNA repair and genome organisation in mammalian cells : studies involving single-cell electrophoresis

    Författare :Stefan Eriksson; Bert van Zeeland; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical Biology; fysikalisk biologi;

    Sammanfattning : The comet assay (single-cell electrophoresis) is a comparably new method for measurement of DNA strand breakage, primarily in eukaryotic cells. Its main advantage is that it works on the single-cell level, making it possible to detect heterogeneity in DNA damage induction and repair. LÄS MER

  2. 17. Regulation of site-selective A-to-I RNA editing : During mammalian brain development

    Författare :Helene Wahlstedt; Marie Öhman; Mary O'connell; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; RNA editering; ADAR; brain development; Molecular biology; Molekylärbiologi; Molecular Biology; molekylärbiologi;

    Sammanfattning : Adenosine (A) to inosine (I) RNA editing is a widespread post-transcriptional mechanism in mammals that contributes to increase the protein diversity. Adenosine deaminases that act on RNA (ADARs) are the enzymes catalyzing RNA editing. ADARs are particularly active within the brain where they act on transcripts involved in neurotransmission. LÄS MER

  3. 18. On strand breakage of DNA in mammalian cells

    Författare :Björn Rydberg; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : .... LÄS MER

  4. 19. Molecular pathways mediating the development of female germ cells

    Författare :Sanjiv Risal; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Ovary; primordial follicles; primordial germ cells; Oogonial stem cells;

    Sammanfattning : In mice, primordial germ cells (PGCs) dramatically increase in their number from 200 cells at 9.5 dpc to 10 000 cells at 12.5 dpc with doubling time of 12.6 hours. LÄS MER

  5. 20. Integration and function of new neurons generated from fibroblasts and adult neural stem cells in the pathological brain

    Författare :James Wood; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurogenesis; neural stem cells; iNs; iPS cells; stroke; epilepsy; electrophysiology;

    Sammanfattning : In Papers One through Six we have investigated the function and integration of “new” neurons – new neurons born from neural stem cells in the adult brain, and new neurons in the sense that they were generated from fibroblasts. Papers One and Two focused on the new neurons generated from neural stem cells in the SVZ and SGZ after pathological insults. LÄS MER