Sökning: "malignant melanoma"

Visar resultat 6 - 10 av 155 avhandlingar innehållade orden malignant melanoma.

  1. 6. Malignant melanoma of the vulva

    Författare :Boel Ragnarsson Olding; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Malignant melanoma; Vulvar melanoma; mucosal melanoma; epidemiology; amelanotic melanoma; pre-existing nevus; N-Ras mutation; TP53 mutation;

    Sammanfattning : From a consecutive, nationwide series of 219 females with primary vulvar malignant melanomas diagnosed in Sweden during 1960 to 1984 and followed up until 1994, we analyzed epidemiological, clinical, histopathological, prognostic and molecular genetic data. The age-standardized incidence among these patients, 75 % of whom were 60 years old or more, decreased by 3. LÄS MER

  3. 7. Genetic characterization of malignant melanoma and breast cancer

    Författare :Göran B Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; oncology; Cytology; microarray; inherited breast cancer; Melanoma; linkage analysis; cancer; Cytologi; cancerology; onkologi;

    Sammanfattning : Malignant melanoma and breast cancer are common malignant diseases characterized by considerable heterogeneity with respect to genetics, histopathology, biology and clinical course. In breast cancer, two major susceptibility genes have been identified, BRCA1 and BRCA2, which account for a significant proportion of high-risk breast cancer families. LÄS MER

  4. 8. Genomic analysis of primary and metastatic malignant melanoma

    Författare :Katja Harbst; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; next-generation sequencing; microarray; progression; molecular grade; subtype; melanoma;

    Sammanfattning : “Cutaneous melanoma is a most unpredictable lesion” wrote Alexander Breslow in 1970. He was one of the first to predict outcome in melanoma patients, based on the thickness of the primary tumor, and today this parameter bears his name and remains the main prognostic factor in melanoma. LÄS MER

  5. 9. Patient and health care delays in malignant melanoma

    Författare :Senada Hajdarevic; Marcus Schmitt-Egenolf; Carol Tishelman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Care seeking; delay; diagnosis; decision making; gender; malignant melanoma; nursing; organization; pathways; severity; Allvarlighetsgrad; att söka vård; beslutsfattande; diagnos; fördröjning; genus; malignt melanom; omvårdnad; organisation; remissvägar; omvårdnadsforskning med medicinsk inriktning; Caring Sciences;

    Sammanfattning : Background: Unlike other cancers, malignant melanoma (MM) is generally visible and can be easily and effectively cured if treated in time. Optimal cure of MM requires early detection, diagnosis, and treatment, which improves prognosis. LÄS MER

  7. 10. Development of individualized surgical treatments for malignant melanoma

    Författare :Valerio Belgrano; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; sentinel node; isolated limb perfusion; immune-humanized xenograft mouse models; translational research;

    Sammanfattning : Background: Cutaneous melanoma is a malignancy with an increasing incidence worldwide, especially in northern Europe. The aim of this thesis is to scrutinize the results achieved by traditional surgery and the opportunities offered by translational research for the more advanced stages of the disease. LÄS MER