Sökning: "malignant melanoma"

Visar resultat 21 - 25 av 155 avhandlingar innehållade orden malignant melanoma.

  1. 21. Exploring the Molecular Landscape of Cutaneous Melanoma

    Författare :Shamik Mitra; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; Immune System; Tumor Microenvironment; Epigenetics; MITF; SOX10;

    Sammanfattning : Cutaneous malignant melanoma (CMM) is one of the most aggressive skin malignancies with poor prognosisfor the patients with metastatic disease. Earlier studies have highlighted the existing molecular diversityamongst CMM tumors. LÄS MER

  3. 22. Cutaneous melanoma in children and adolescents and aspects of naevus phenotype in melanoma risk assessment

    Författare :Pia Karlsson; Inger Rosdahl; Johan Hansson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; melanoma; naevus; childhood; adolescence; prevention; epidemiology; Dermatology and venerology; Dermatologi och venerologi;

    Sammanfattning : Cutaneous malignant melanoma (CMM) is one of the most rapidly increasing cancers in the Swedish population. The aetiology of melanoma is a complex interplay between genetics, host characteristics and environmental factors. LÄS MER

  4. 23. Molecular genetics of cutaneous malignant melanoma

    Författare :Malihe Eskandarpour; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cutaneous malignant melanoma is an aggressive tumor of melanocytes in the skin with rapidly increasing incidence. Patients with advanced disease have a poor prognosis since the tumor is usually resistant to current therapies. Therefore, the development of novel strategies for preventing and treating melanoma is important. LÄS MER

  5. 24. Malignant melanoma-Risk factors and the CDKN2A mutation in relation to phenotypes and other cancers

    Författare :Kari Nielsen; Lund Dermatologi och venereologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; clinically atypical nevus; nevus; CDKN2A; melanoma; risk factors; sunbed; UVR;

    Sammanfattning : Background: Cutaneous malignant melanoma (CMM) is an increasingly common cancer in fair-skinned people. The purpose of this thesis was to study high-risk patients with multiple tumours including a CMM, high-risk families with the unique Swedish germline mutation in CDKN2A(113insArg), as well as study risk factors for CMM in women. LÄS MER

  7. 25. The Role of Melanocyte Lineage Genes in Melanoma

    Författare :Adriana Sanna; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanoma; Genetic; Epigenetic; Heterogeneity; MITF; SOX10; CSD;

    Sammanfattning : Malignant melanoma accounts for the highest number of deaths among all skin cancer types, and its incidence has increased dramatically over the past decades. Despite the tremendous therapeutic advances, treatment resistant cells emerge in the vast heterogeneity of melanoma, driving tumor relapse and poor patient outcome. LÄS MER